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Diclofenac sodium

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Identification
Molecular formula
C14H10Cl2NO2Na
CAS number
15307-79-6
IUPAC name
sodium;2-[2-(2,6-dichloroanilino)phenyl]acetate
State
State
At room temperature, diclofenac sodium is a solid that is incorporated in many pharmaceutical forms. Although it is stable at room temperature, it should be kept in a well-sealed container to prevent moisture absorption. The compound is typically soluble in methanol and ethanol, but insoluble in water.
Melting point (Celsius)
283.00
Melting point (Kelvin)
556.15
Boiling point (Celsius)
306.30
Boiling point (Kelvin)
579.45
General information
Molecular weight
318.14g/mol
Molar mass
318.1370g/mol
Density
1.2500g/cm3
Appearence
Diclofenac sodium appears as a white to off-white, slightly hygroscopic crystalline powder. It is often found in pharmaceutical formulations such as tablets or topical gels. The compound is known for its slight odor and is typically taste bitter.
Comment on solubility

Solubility of Sodium 2-[2-(2,6-dichloroanilino)phenyl]acetate

Sodium 2-[2-(2,6-dichloroanilino)phenyl]acetate, a complex organic compound, exhibits notable solubility characteristics.

Solubility in Water

This compound is generally considered to be soluble in water due to the presence of the sodium ion, which increases its ability to interact with water molecules. The ionic nature of the sodium component promotes dissolution, allowing it to be utilized effectively in various aqueous environments.

Factors Influencing Solubility

  • Temperature: Increased temperature often enhances the solubility of organic compounds.
  • pH: The solubility can also be influenced by the pH of the solution, as certain protonation states may affect the compound's interactions.
  • Presence of Solvents: Solubility is relative to the nature of co-solvents present in the solution. For instance, organic solvents might reduce solubility in comparison with water.

Practical Implications

Understanding the solubility of sodium 2-[2-(2,6-dichloroanilino)phenyl]acetate is crucial for applications in pharmaceuticals and chemical synthesis. The compound's behavior in solution can significantly influence its efficacy and interactions.

In summary, the solubility of this compound demonstrates the impact of ionic strength and environmental conditions, providing insights into its potential applications in various fields.

Interesting facts

Interesting Facts About Sodium; 2-[2-(2,6-dichloroanilino)phenyl]acetate

Sodium; 2-[2-(2,6-dichloroanilino)phenyl]acetate is a fascinating compound known for its multifaceted applications in the field of medicinal chemistry and industrial processes. Here are some intriguing aspects of this compound:

  • Complex Structure: This compound contains a unique blend of functionalities, incorporating both aromatic and aliphatic groups, which contributes to its diverse reactivity and interactions in chemical reactions.
  • Pharmaceutical Relevance: The presence of the 2,6-dichloroanilino moiety suggests potential bioactivity. Compounds containing anilines often have applications in drug design due to their biological activities.
  • Sodium Salt Form: As a sodium salt, it offers enhanced solubility in water compared to its parent acid, making it easier to utilize in various reactions and applications.
  • Research Interest: The structural components of this compound make it a subject of interest in research focused on the synthesis of novel pharmaceuticals, enabling the exploration of new therapeutic avenues.
  • Environmental Concerns: With the introduction of halogens, such as chlorine, in its structure, studies regarding its environmental impact and degradation pathways are essential for understanding its lifecycle and safety.

In summary, sodium; 2-[2-(2,6-dichloroanilino)phenyl]acetate not only showcases a complex chemical nature but also presents significant implications in medicinal chemistry and environmental studies, making it a noteworthy compound for further exploration.