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Iopamidol

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Identification
Molecular formula
C17H22I3N3O8
CAS number
60166-93-0
IUPAC name
sodium;2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]butanoate
State
State

At room temperature, Iopamidol is typically in a solid state as a crystalline powder. When prepared as an injection solution, it is in a liquid state.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.00
Boiling point (Celsius)
262.00
Boiling point (Kelvin)
535.00
General information
Molecular weight
777.09g/mol
Molar mass
777.0880g/mol
Density
2.2830g/cm3
Appearence

Iopamidol is typically a white to off-white crystalline powder. It is highly soluble in water, which gives it a clear to slightly opalescent solution when dissolved. As it's used as a contrast agent, the solutions are specifically prepared to be sterile and pyrogen-free.

Comment on solubility

Solubility of sodium; 2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]butanoate

The solubility of sodium; 2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]butanoate is an important characteristic, especially given the presence of both sodium and iodine in its structure. Understanding its solubility can be approached from several angles:

  • Solubility in Water: The sodium salt format typically suggests a higher degree of solubility in water, allowing it to readily dissociate into sodium ions and the corresponding anion in aqueous solutions.
  • Hydrophilic and Hydrophobic Properties: The presence of the butanoate group can enhance hydrophilicity due to its polar -COO- group, while the triiodo substitution might contribute to some hydrophobic characteristics due to iodine's size and lower electronegativity.
  • Temperature Dependence: Like many organic compounds, solubility may vary with temperature, typically increasing as the temperature rises.
  • pH Influence: As with carboxylate salts, the solubility can be affected by the pH of the solution, with higher solubility observed in more basic conditions.

In conclusion, the solubility profile of sodium; 2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]butanoate illustrates the complex interplay of molecular structure and environmental factors. This aids in predicting its behavior in various chemical environments, making it essential for practical applications.

Interesting facts

Interesting Facts about Sodium; 2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]butanoate

Sodium; 2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]butanoate is a fascinating compound that presents a unique combination of elements and functionalities. Its intricate structure opens the door to numerous implications in both the scientific and medical fields. Here are a few notable aspects worth exploring:

  • Medical Imaging: The presence of iodine in this compound allows it to be used in medical imaging techniques, particularly in X-ray imaging and . Iodine functions as a contrast agent, enhancing the visibility of internal structures.
  • Pyrrolidine Influence: The 2-oxopyrrolidin-1-yl moiety contributes to the drug-like properties of this compound. Pyrrolidinyl compounds are often associated with analgesic and antidepressant activities in medicinal chemistry.
  • Structure-Activity Relationship: The unique arrangement of the phenyl ring coupled with the butanoate side-chain plays a crucial role in determining the biological activity of this compound. It highlights the importance of structural motifs in pharmacology.
  • Research Potential: Due to its complex structure, this compound is a prime candidate for structure-activity relationship studies which aim to optimize its therapeutic efficacy.

In summary, sodium; 2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]butanoate is more than just a chemical formula; it represents a crossroads of chemistry, medicine, and innovation. As stated in a classic chemistry axiom, “The more we study, the more we realize the complexity and beauty of Nature's creations.” This compound is a wonderful example of that complexity and a reminder of the exciting discoveries that lie ahead!