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Iopamidol

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Identification
Molecular formula
C17H22I3N3O4Na
CAS number
60166-93-0
IUPAC name
sodium;2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoate
State
State

At room temperature, iopamidol typically exists as a solid. When used in medical applications, it is usually dissolved in an appropriate solvent to form a liquid solution for use as a contrast agent in diagnostic imaging.

Melting point (Celsius)
269.00
Melting point (Kelvin)
542.15
Boiling point (Celsius)
395.00
Boiling point (Kelvin)
668.15
General information
Molecular weight
777.09g/mol
Molar mass
777.0880g/mol
Density
1.4500g/cm3
Appearence

Iopamidol appears as a white or almost white crystalline powder. It is odorless and relatively stable under normal conditions. The compound is used primarily as a contrast agent in medical imaging and its solid form is typically highly purified for this purpose.

Comment on solubility

Solubility of Sodium 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoate

The solubility of sodium 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoate can be influenced by various factors, primarily its unique chemical structure. Here are some notable aspects regarding its solubility:

  • Water Solubility: Sodium salts typically exhibit good solubility in water. This compound, being a sodium salt, is expected to dissolve readily in aqueous solutions.
  • Influence of Iodine: The presence of multiple iodine atoms in the aromatic ring can alter solubility. Iodine can introduce hydrophobic characteristics, which may affect the overall water solubility.
  • Polarity Factors: The butanoylamino and butanoate groups contribute polar functional properties, likely enhancing solubility in polar solvents.
  • pH Dependency: The solubility may vary with changes in pH. In acidic conditions, protonation of amino groups could affect solubility, while in basic conditions, deprotonation could enhance it.
  • Temperature Effects: Typical of many compounds, increased temperature might increase solubility; thus, a temperature-dependent solubility study would provide more detailed insights.

In summary, while sodium 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoate is anticipated to be soluble in water due to its sodium ion presence, various structural factors and environmental conditions will ultimately dictate the extent and nature of its solubility.

Interesting facts

Interesting Facts about Sodium; 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoate

This intriguing compound, known as sodium; 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoate, presents a fascinating intersection of organic chemistry and medicinal applications. Here are some interesting highlights:

  • Complex Structure: The compound features a complex molecular framework that includes a triiodo-phenyl group. This unique arrangement allows it to have specific interactions with biological systems, enhancing its functional capabilities.
  • Medical Relevance: Compounds like this are often explored for their potential applications in pharmacology. Due to the presence of iodine atoms, which are known for their radiological properties, it may have applications in imaging or radiotherapy.
  • Butanoylamino Group: The butanoylamino moiety is particularly notable as it can influence the solubility and biological activity of the compound, making it a prime candidate for research into drug design.
  • Sodium Salt Form: As a sodium salt, this compound is likely to exhibit improved stability and bioavailability compared to its non-salt counterparts, a crucial factor when designing compounds intended for therapeutic use.
  • Research Potential: Studies focusing on compounds with similar structures are ongoing, potentially leading to breakthroughs in targeted therapies for various diseases, including cancer.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” The exploration of such compounds exemplifies this philosophy, paving the way for exciting discoveries in the world of chemistry and medicine.