Sodium taurocholate | Solubility of Things

Identification

Molecular formula

C₂₆H₄₄NO₇SNa

CAS number

145-42-6

IUPAC name

sodium;2-[4-(3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetate

State

At room temperature, sodium taurocholate is a solid substance, typically found in its crystalline form.

Melting point (Celsius)

298.00

Melting point (Kelvin)

571.15

Boiling point (Celsius)

1 194.15

Boiling point (Kelvin)

1 467.15

General information

Molecular weight

537.70g/mol

Molar mass

537.6960g/mol

Density

1.2750g/cm³

Appearence

Sodium taurocholate is typically a white or off-white crystalline powder. It is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of Sodium 2-[4-(3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetate

The solubility of sodium 2-[4-(3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetate is influenced by several factors:

Polarity: Due to the presence of sodium and multiple functional groups, the compound exhibits polar characteristics, which can enhance its solubility in polar solvents, such as water.
Hydrogen Bonding: The multiple hydroxyl (-OH) groups in its structure can form hydrogen bonds with water molecules, further contributing to its solubility.
Chain Length: The lengthy hydrophobic hydrocarbon tail may reduce solubility in very polar solvents, limiting the compound’s dissolution in such mediums.
Temperature Dependence: Like many organic compounds, solubility can vary with temperature, often increasing with higher temperatures.

It is essential to note that while sodium salts generally demonstrate increased solubility compared to their acid forms, the complex nature of this compound may lead to varying degrees of solubility based on the specific solvent and conditions. As such, practical solubility assessments are best determined through experimental measurements.

Interesting facts

Interesting Facts about Sodium 2-[4-(3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetate

This compound, known for its complex structure, showcases the fascinating intersections of biochemistry and medicinal chemistry. Here are some captivating insights:

Structural Complexity: The presence of a tetradecahydro-cyclopenta[a]phenanthren core makes this compound particularly interesting for scientists studying sterols and hormones. The intricate arrangement of the hydroxy groups adds to its reactivity and potential biological activities.
Potential Biological Activity: Compounds derived from structures similar to this one have been implicated in various biological processes, including hormone regulation and potential pharmaceutical applications. As such, studying its mechanisms could yield valuable insights into therapeutic uses.
Functionality of the Acetate Group: The acetate moiety can enhance solubility and stability of the compound, making it more suitable for biological studies. Understanding how this group interacts with cellular receptors could lead to advancements in drug design.
Sodium’s Role: The sodium ion in the compound is essential for many biological functions, from regulating cellular physiology to enhancing the compound's stability and solubility in aqueous environments. This ionic form often facilitates the absorption and transport of the molecule in biological systems.

"Understanding the interplay between structure and function is vital in the development of effective therapeutic agents."

This compound serves as a remarkable example of how chemical simplicity can lead to complex biological implications. Researchers continuously explore ways to utilize such compounds in combating diseases and enhancing human health.