Sodium taurocholate | Solubility of Things

Identification

Molecular formula

C₂₆H₄₄NO₇SNa

CAS number

145-42-6

IUPAC name

sodium;2-[4-[(3R,7R,12S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]ethanesulfonate

State

At room temperature, sodium taurocholate exists as a solid. It is stable under normal conditions but should be stored in a dry place to prevent moisture absorption. Sodium taurocholate is highly soluble in water.

Melting point (Celsius)

296.00

Melting point (Kelvin)

569.00

Boiling point (Celsius)

671.00

Boiling point (Kelvin)

944.00

General information

Molecular weight

537.69g/mol

Molar mass

537.6870g/mol

Density

1.4900g/cm³

Appearence

Sodium taurocholate is typically a white to off-white powder or a crystalline solid. It is hygroscopic, meaning it can absorb moisture from the environment, which can cause it to clump or stick together.

Comment on solubility

Solubility of Sodium 2-[4-[(3R,7R,12S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]ethanesulfonate

The solubility of sodium 2-[4-[(3R,7R,12S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]ethanesulfonate is primarily influenced by its structural characteristics. Here’s what can be noted regarding its solubility:

Polar Nature: Due to the presence of multiple hydroxyl (-OH) groups and sulfonate groups, this compound exhibits a polar character, which generally enhances its solubility in polar solvents.
Water Solubility: Given that it is a sodium salt, it is likely to be soluble in water, a common characteristic of most salts.
Influence of Molecular Size: The extensive hydrophobic region contributed by the tetradecahydro structure may affect solubility. As a result, it may be less soluble in non-polar solvents compared to polar solvents.
pH Dependence: Solubility can also be influenced by the pH of the solution; alterations may affect the ionization of functional groups.

Overall, the solubility behavior of this compound can be summarized as:
- **Good solubility in polar solvents, particularly water**
- **Limited solubility in non-polar solvents**
- **Potentially pH-dependent solubility characteristics**

These factors play a crucial role in determining how this compound interacts in various formulations and environments.

Interesting facts

Interesting Facts about Sodium 2-[4-[(3R,7R,12S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]ethanesulfonate

Sodium 2-[4-[(3R,7R,12S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]ethanesulfonate is a fascinating compound with a unique structural configuration and a variety of applications in biochemistry and medicinal chemistry. Below are some intriguing aspects of this compound:

Bioactivity: This compound is often associated with bioactivity, playing a role in various biological processes. Researchers are investigating its potential effects on metabolic pathways and cellular functions.
Structural Complexity: The detailed structure of this compound features multiple functional groups, which are crucial for its biological interaction. The presence of hydroxyl groups adds to its potential reactivity and solubility.
Potential Applications: Sodium 2-[4-[(3R,7R,12S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]ethanesulfonate might be explored in drug formulation, especially in designing molecules that target specific receptors, showcasing the intersection of chemistry and pharmacology.
Research Focus: Scientists are actively studying the role of similar compounds in therapeutic contexts, particularly in relation to diseases linked with hormonal imbalances and metabolic disorders.
Amino Acid Linkage: The compound features an amino acid moiety, which could contribute to its effectiveness as a drug or a biochemical tool, aiding in targeting specific biological receptors or pathways.
Ethansulfonate Group: The presence of an ethanesulfonate group indicates its possible ionizable properties, which could enhance its interaction with biological molecules.

In conclusion, Sodium 2-[4-[(3R,7R,12S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]ethanesulfonate stands as a testament to the complexity and creativity found in organic chemistry, opening new avenues for discovery and exploration in biochemical research.