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Naproxen sodium

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Identification
Molecular formula
C14H13NaO3
CAS number
26159-34-2
IUPAC name
sodium;2-(6-methoxy-2-naphthyl)propanoate
State
State

At room temperature, Naproxen sodium is in a solid state, typically existing as a white crystalline powder.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
265.50
Boiling point (Kelvin)
538.65
General information
Molecular weight
252.24g/mol
Molar mass
252.2410g/mol
Density
1.2290g/cm3
Appearence

Naproxen sodium appears as a white to creamy white crystalline powder. It is odorless or may have a slight characteristic odor.

Comment on solubility

Solubility of Sodium 2-(6-methoxy-2-naphthyl)propanoate (C14H13NaO3)

Sodium 2-(6-methoxy-2-naphthyl)propanoate exhibits interesting solubility characteristics due to its ionic nature as a sodium salt. Here are some key points about its solubility:

  • Water Solubility: Being a sodium salt, it is expected to be highly soluble in water. This solubility is primarily due to the ability of the sodium ion (Na+) to interact favorably with water molecules.
  • Organic Solvents: The presence of the naphthyl and methoxy groups may impart some degree of solubility in organic solvents, particularly in polar organic solvents like methanol and ethanol.
  • pH Dependence: The solubility might also vary with pH levels; typically, the anionic lipophilic nature of the compound can lead to decreased solubility in highly alkaline or acidic environments.
  • Temperature Influence: Higher temperatures can enhance the solubility of sodium 2-(6-methoxy-2-naphthyl)propanoate in both water and organic media due to increased molecular mobility.

In summary, sodium 2-(6-methoxy-2-naphthyl)propanoate is likely to possess significant solubility in various mediums, making it versatile for chemical applications. Its effective solubility can be crucial for its reactivity and interaction in different chemical environments.

Interesting facts

Exploring Sodium 2-(6-Methoxy-2-Naphthyl)propanoate

Sodium 2-(6-methoxy-2-naphthyl)propanoate is a fascinating compound that combines the properties of sodium salt with an aromatic naphthalene derivative. Here are some compelling facts about this compound:

  • Pharmaceutical Applications: This compound is often explored in pharmaceutical research due to its potential anti-inflammatory and analgesic properties. The naphthalene structure plays a significant role in the biological activity.
  • Structure and Function: The unique configuration of 2-(6-methoxy-2-naphthyl)propanoate contributes to its reactivity and interactions with biological targets. Its molecular structure enables a variety of functionalizations, making it a versatile scaffold in medicinal chemistry.
  • Solubility Considerations: As a sodium salt, it generally exhibits better solubility in aqueous environments compared to its parent organic acid. This property is crucial for its bioavailability and efficacy in therapeutic contexts.
  • Analytical Importance: Sodium 2-(6-methoxy-2-naphthyl)propanoate can be used as a standard in analytical chemistry. It helps in calibrating methods for detecting similar compounds and assessing their purity and concentration.

In the words of a prominent chemist, "The beauty of chemistry lies in the unexpected relations and results we can glean from seemingly simple compounds." As we delve deeper into sodium 2-(6-methoxy-2-naphthyl)propanoate, we uncover its intricate role in the vast universe of organic and medicinal chemistry.

Conclusion

With its intriguing structural features and promising applications, sodium 2-(6-methoxy-2-naphthyl)propanoate stands as a testament to the dynamism of chemical research. Whether in laboratories or the realms of pharmaceutical design, this compound continues to captivate the minds of scientists worldwide.

Synonyms
sodium 2-(6-methoxynaphthalen-2-yl)propanoate
55577-80-5
starbld0018929
SCHEMBL2472355
CHEMBL1903819
HMS3371G21
HMS3373O06
HMS3394G05
HMS3655K11
HMS3677P03
BCP23430
AKOS015960654
NCGC00167815-01
AC-12017
SY331367
NS00084049
Sodium (S)-2-(6-Methoxy-2-naphthyl)propanoate
sodium (+/-)-2-(6-methoxy-2-naphthyl)propionate