Sodium hippurate | Solubility of Things

Identification

Molecular formula

C₉H₈NO₃Na

CAS number

15291-77-7

IUPAC name

sodium;2-benzamidoacetate

State

At room temperature, sodium hippurate is a solid. It is stable under standard conditions and commonly used in its solid crystalline form.

Melting point (Celsius)

208.00

Melting point (Kelvin)

481.15

Boiling point (Celsius)

359.10

Boiling point (Kelvin)

632.30

General information

Molecular weight

195.17g/mol

Molar mass

195.1740g/mol

Density

1.1800g/cm³

Appearence

Sodium hippurate is a white crystalline powder. It is soluble in water and has a mild odor. The solid is typically in the form of fine crystals or powder.

Comment on solubility

Solubility of Sodium 2-Benzamidoacetate

Sodium 2-benzamidoacetate, a salt derived from the reaction of 2-benzamidoacetic acid with sodium, exhibits intriguing solubility characteristics that are essential for its applications. Its solubility can be influenced by various factors, including:

Polarity: As an ionic compound, sodium 2-benzamidoacetate is likely to be soluble in polar solvents such as water due to the interaction between the sodium ions and the solvent molecules.
Temperature: Increased temperatures generally enhance the solubility of solid compounds in liquids. Thus, heating the solution can facilitate the dissolution of sodium 2-benzamidoacetate.
pH of the Solution: The solubility may also be affected by the pH levels, where an alkaline environment could potentially increase solubility due to deprotonation reactions.

In general, the solubility of sodium 2-benzamidoacetate is moderate. According to some sources, it is stated that:

“Sodium salts often show better solubility in water compared to their corresponding acids.”

This underscores the notion that sodium 2-benzamidoacetate is expected to dissolve reasonably well in aqueous solutions, contributing to its utility in various chemical applications. Its solubility behavior is crucial for understanding its reactivity and potential use in pharmaceutical formulations, quality control, and other chemical processes.

Interesting facts

Interesting Facts about Sodium 2-benzamidoacetate

Sodium 2-benzamidoacetate is a fascinating compound that combines both sodium ions and a benzamidoacetate structure, which brings unique properties and applications. Here are some intriguing aspects of this chemical:

Biological Relevance: This compound has been studied for its potential biological activities, which could play a crucial role in drug development and biochemical research.
Role in Organic Synthesis: Sodium 2-benzamidoacetate can serve as an effective reagent in organic synthesis, particularly in the formation of amide bonds, which are essential in creating a variety of pharmaceutical compounds.
Potential Antimicrobial Properties: Some studies suggest that compounds similar to sodium 2-benzamidoacetate may exhibit antimicrobial properties, making them valuable in the fight against resistant bacterial strains.
Versatile Applications: Beyond its role in synthesis and potential medicinal uses, sodium 2-benzamidoacetate can also be applied in biochemical assays, enhancing researchers’ ability to probe metabolic pathways.
Contributing to Green Chemistry: The use of sodium in the formulation encourages sustainable practices, promoting reactions that are often safer and more environmentally friendly compared to some traditional methods.

In conclusion, the unique combination of sodium and the benzamidoacetate moiety in sodium 2-benzamidoacetate makes it an important candidate for further studies. As research continues, this compound may unveil even more fascinating attributes and applications in various fields of chemistry and medicine.