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Ioxitalamic acid sodium salt

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Identification
Molecular formula
C11H8I3NaNO4
CAS number
22766-35-2
IUPAC name
sodium;2-phenyl-2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenoxy]acetate
State
State

At room temperature, it exists as a solid. It is usually found in its salt form, which enhances its solubility in water, making it suitable for medical applications.

Melting point (Celsius)
229.00
Melting point (Kelvin)
502.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
821.87g/mol
Molar mass
821.9650g/mol
Density
2.2820g/cm3
Appearence

Ioxitalamic acid sodium salt is typically a fine, crystalline powder that is white to off-white in color. It is often used as a contrast agent in medical imaging, and in its pure form, it is colorless and dissolves in water to form a clear, colorless solution.

Comment on solubility

Solubility of Sodium 2-phenyl-2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenoxy]acetate

The solubility of sodium 2-phenyl-2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenoxy]acetate is influenced by several factors, given its complex structure. Generally, one can consider the following aspects:

  • Polarity: The presence of ionic sodium and various functional groups suggests that this compound may exhibit higher solubility in polar solvents.
  • Hydrophilic and Hydrophobic Balance: The molecule features both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, which can affect solubility in different solvent environments.
  • Temperature Influence: Solubility often increases with temperature; thus, a higher temperature may enhance the dissolution of this compound in solvent systems.
  • pH Effects: As a salt of an organic acid, changes in pH can significantly impact solubility, potentially increasing solubility in more alkaline conditions.

In practice, employing solvent mixtures or modifying conditions can tailor solubility properties to suit specific applications or desired reactions. It's crucial to note that while the sodium salt form typically increases solubility in water, experimental data are imperative for precise understanding.

Interesting facts

Interesting Facts about Sodium 2-Phenyl-2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenoxy]acetate

This unique compound is an intriguing example of a iodinated phenoxyacetate that has drawn significant attention in various fields of research. Here are several key facts that highlight its importance:

  • Pharmaceutical Applications: Due to its structural properties, this compound has potential uses in pharmacology, particularly in designing new drugs with targeted action. Its phenyl and triiodophenyl groups may enhance its interaction with biological targets.
  • Radiological Significance: The presence of iodine makes this compound a candidate for application in radiological imaging. Iodine is well-known for its radio-opacity, which can be highly beneficial in medical imaging techniques such as X-rays and CT scans.
  • Synthesis Complexity: The synthesis of sodium 2-phenyl-2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenoxy]acetate is quite elaborate, often requiring advanced methods such as multi-step organic synthesis. This complexity not only highlights the ingenuity of chemists but also underscores the potential for discovering new chemical pathways.
  • Biological Research: Its link to pyrrolidine derivatives indicates a potential for pharmacological utility, especially in examining aspects of neurotransmission and other biological interactions. Researchers are keenly interested in how such compounds influence biological systems at a molecular level.
  • Caution in Use: As with many synthetic compounds, proper handling and understanding of its toxicity and environmental impact are crucial. Scientists stress the importance of conducting thorough risk assessments during its application in research or pharmaceuticals.

In conclusion, sodium 2-phenyl-2-[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenoxy]acetate stands as a multifaceted compound with diverse implications in both scientific research and applied chemistry. Its combination of iodine and unique molecular structure offers pathways for further exploration and discovery.