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Sodium difluoroacetate

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Identification
Molecular formula
C2HF2NaO2
CAS number
675-50-5
IUPAC name
sodium;2,2-difluoroacetate
State
State

At room temperature, sodium difluoroacetate is in a solid state, existing as a dry, stable crystalline powder.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
174.80
Boiling point (Kelvin)
447.95
General information
Molecular weight
122.02g/mol
Molar mass
122.0180g/mol
Density
1.4480g/cm3
Appearence

Sodium difluoroacetate typically appears as a white crystalline powder. It is highly soluble in water and has a slightly acrid odor.

Comment on solubility

Solubility of Sodium 2,2-Difluoroacetate

Sodium 2,2-difluoroacetate, with the chemical formula NaC2H2F2O2, demonstrates interesting solubility characteristics that merit attention.

Key Solubility Properties:

  • Highly Soluble in Water: This compound is known for its high solubility in water, typically dissolving readily due to the ionic nature of sodium (Na+) and the polar characteristics of the difluoroacetate anion.
  • Temperature Influence: Like many salts, the solubility of sodium 2,2-difluoroacetate can increase with temperature, promoting even greater dissolution in warmer water.
  • Solvent Specificity: While it is predominantly soluble in aqueous solutions, the solubility behavior in non-polar solvents can be quite different. In general, its solubility decreases significantly in solvents like ethanol or hexane.

As a rule of thumb, if you are considering its use in various reactions or applications, remember:
* “Like dissolves like.” This principle can guide your expectations regarding solubility.
* In case of any difficulties with dissolution, increasing temperature may help achieve the desired concentration.

In summary, sodium 2,2-difluoroacetate’s notable water solubility lends itself well to various applications, particularly in aqueous-based systems. For chemists and researchers, being aware of these solubility nuances is crucial for effective experimentation and formulation.

Interesting facts

Interesting Facts about Sodium 2,2-Difluoroacetate

Sodium 2,2-difluoroacetate is a fascinating compound that plays a unique role in both organic chemistry and biochemistry. Here are some intriguing aspects of this compound:

  • Fluorinated Compounds: The presence of fluoro groups in this compound enhances its reactivity and alters the physical properties, making it a valuable substance in pharmaceutical synthesis.
  • Biochemical Applications: Sodium 2,2-difluoroacetate has been studied for its potential utility in metabolic studies, particularly due to its effects on various enzymatic reactions.
  • Versatile Precursor: It is often used as a building block in organic synthesis, especially in the preparation of difluorinated compounds, which can lead to novel drugs and agrochemicals.
  • Ecological Considerations: While fluorinated compounds can be beneficial in many applications, their environmental impact is a subject of ongoing research, highlighting the need for responsible use and disposal.
  • Research Insights: Studies involving sodium 2,2-difluoroacetate have provided insights into the mechanisms of action of various metabolic pathways, showcasing the intricate connections between chemistry and biology.

In summary, sodium 2,2-difluoroacetate serves not only as a key component in chemical synthesis but also as a valuable tool in scientific research, illustrating the profound connections between chemistry and the life sciences.