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Sodium Levofolinate

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Identification
Molecular formula
C20H23N7NaO7P
CAS number
1492-18-8
IUPAC name
sodium;[(2S,3R,4R)-5-(7,8-dimethyl-2,4-dioxo-benzo[g]pteridin-10-yl)-2,3,4-trihydroxy-pentyl] hydrogen phosphate
State
State

At room temperature, sodium levofolinate is usually found as a solid in the form of its crystalline powder. It is stable under normal conditions but should be kept dry to avoid moisture absorption.

Melting point (Celsius)
150.50
Melting point (Kelvin)
423.65
Boiling point (Celsius)
232.00
Boiling point (Kelvin)
505.15
General information
Molecular weight
533.40g/mol
Molar mass
511.1710g/mol
Density
1.3000g/cm3
Appearence

Sodium levofolinate is typically a white to off-white crystalline powder. It is known for being hygroscopic, which means it can absorb moisture from the environment. However, in its stable form, it maintains a distinct crystalline structure.

Comment on solubility

Solubility of Sodium;[(2S,3R,4R)-5-(7,8-dimethyl-2,4-dioxo-benzo[g]pteridin-10-yl)-2,3,4-trihydroxy-pentyl] Hydrogen Phosphate

This compound presents an intriguing profile when it comes to solubility. The presence of sodium ions typically indicates a certain level of water solubility, as sodium salts are generally more soluble compared to their corresponding acids. However, the overall solubility of this specific compound can be influenced by several factors:

  • Molecular Structure: The complex structure, especially with the functional groups such as hydroxyls and phosphate, can significantly alter solubility in polar solvents like water.
  • Polarity: The tri-hydroxy and phosphate groups enhance its polarity, likely leading to increased solubility in aqueous solutions.
  • Intermolecular Interactions: Hydrogen bonding capabilities due to hydroxyl groups may promote solvation, thus influencing overall solubility.

“Solubility is not just the presence of a solvent; it's a dance of forces between molecules.” This quote captures the nuanced nature of solubility in compounds like this. While the sodium component suggests potential solubility, the complexity of the pteridin structure may create variations under different conditions.

In summary, while sodium salts are generally soluble, the intricate balance of polarity, molecular interactions, and structural features will ultimately determine the solubility of sodium;[(2S,3R,4R)-5-(7,8-dimethyl-2,4-dioxo-benzo[g]pteridin-10-yl)-2,3,4-trihydroxy-pentyl] hydrogen phosphate in various solvents.

Interesting facts

Interesting Facts about Sodium [(2S,3R,4R)-5-(7,8-dimethyl-2,4-dioxo-benzo[g]pteridin-10-yl)-2,3,4-trihydroxy-pentyl] Hydrogen Phosphate

This compound may appear complex at first glance due to its intricate structure, but it provides fascinating insights into its applications and significance in various fields. Here are some noteworthy aspects:

  • Biological Role: Sodium, in its various forms, plays a crucial role in numerous biological processes, including nerve impulse transmission and muscle contraction. This compound, particularly with the benzo[g]pteridin moiety, may have specific implications in biochemical pathways, potentially involved in signaling mechanisms.
  • Potential Therapeutic Applications: The presence of the benzo[g]pteridin structure suggests possible avenues for research related to pharmacology. Pteridines are known for their antioxidant properties and may have applications in treating oxidative stress-related disorders.
  • Structure-Activity Relationship: Understanding the stereochemistry, such as the (2S,3R,4R) configuration, is critical in medicinal chemistry. This stereochemistry can influence the compound's biological activity, making it a vital area of study.
  • Phosphate Groups: The inclusion of phosphate groups in the compound can enhance solubility and bioavailability, which could affect how the body processes this compound and its efficiency as a therapeutic agent.

In summary, sodium [(2S,3R,4R)-5-(7,8-dimethyl-2,4-dioxo-benzo[g]pteridin-10-yl)-2,3,4-trihydroxy-pentyl] hydrogen phosphate is not just a chemical compound; it represents a bridge between chemistry and biology, opening new doors for research and understanding of complex biological systems. As we continue to investigate this compound, its potential benefits are bound to unveil new possibilities in science and medicine.