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Dexamethasone sodium phosphate

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Identification
Molecular formula
C22H28FNa2O8P
CAS number
2392-39-4
IUPAC name
sodium;3-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]carbonylbenzenesulfonate
State
State

At room temperature, dexamethasone sodium phosphate is typically in a solid crystalline state. However, it may be formulated into liquid solutions or suspensions for medical administration purposes.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
516.43g/mol
Molar mass
516.4330g/mol
Density
1.4500g/cm3
Appearence

Dexamethasone sodium phosphate typically appears as a white or slightly yellow crystalline powder. It may also be available as a colorless, transparent aqueous solution when prepared for medical use.

Comment on solubility

Solubility of Sodium 3-[2-(11,17-Dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]carbonylbenzenesulfonate

The solubility of sodium 3-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]carbonylbenzenesulfonate is influenced by several factors due to its complex structure. Here are some key points to consider:

  • Polarity: This compound possesses both hydrophilic (water-attracting) and hydrophobic (water-repelling) components, which can affect its overall solubility in aqueous solutions.
  • Effect of Sodium Ion: The presence of sodium enhances solubility in water due to ionic interactions, typically leading to increased solubility of sulfonate-containing compounds.
  • Temperature Dependency: Like many chemical compounds, solubility may increase with temperature, making higher temperatures more favorable for dissolving this particular substance.
  • Influence of pH: The surrounding pH of the solution can also play a significant role in solubility, particularly if the compound can ionize or react with hydrogen ions.

In conclusion, the solubility of this compound is a prime example of how structural features interact with environmental conditions. Understanding these interactions can lead to more effective applications and improved formulations.

Interesting facts

Interesting Facts about Sodium 3-[2-(11,17-Dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]carbonylbenzenesulfonate

This compound presents a fascinating intersection of organic chemistry and medicinal applications. Its structural complexity highlights the versatility of chemical compounds in designing pharmaceuticals.

Key Highlights:

  • Nature-Inspired Design: The compound's backbone is inspired by natural steroid frameworks, making it a potential candidate for various biological activities, particularly in the field of endocrinology.
  • Functional Groups: The presence of multiple functional groups, such as hydroxyl, carbonyl, and sulfonate, suggests diverse reactivity and interactions, opening avenues for derivative synthesis.
  • Pharmacological Potential: Given its steroid-like structure, it has been studied for effects on hormonal regulation and as a possible therapeutic agent in treating hormonal imbalances and related diseases.
  • Ecological Chemistry: The sulfonate group in its structure provides significant ecological interest, as it can influence the compound's solubility and interaction with various biological systems.

As a chemistry student or scientist delving into this compound, one might consider:

  • How might the synthesis of this compound be approached in a laboratory setting?
  • What role do the stereochemistry and spatial orientation of functional groups play in its biological activity?
  • How can this compound be modified to enhance its effectiveness or reduce potential side effects?

In conclusion, the sodium 3-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]carbonylbenzenesulfonate compound exemplifies the endless possibilities within organic chemistry and its applications in healthcare. Its unique characteristics make it a rich subject for study and exploration.