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Nabumetone

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Identification
Molecular formula
C15H16O2
CAS number
42924-53-8
IUPAC name
sodium;3-[(4-nitrophenyl)carbamoylamino]propanoate
State
State

At room temperature, nabumetone is in a solid state as a crystalline powder.

Melting point (Celsius)
80.50
Melting point (Kelvin)
353.70
Boiling point (Celsius)
507.10
Boiling point (Kelvin)
780.30
General information
Molecular weight
228.29g/mol
Molar mass
228.2540g/mol
Density
1.4072g/cm3
Appearence

Nabumetone appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of Sodium 3-[(4-nitrophenyl)carbamoylamino]propanoate

Sodium 3-[(4-nitrophenyl)carbamoylamino]propanoate, a compound with a complex structure, exhibits interesting solubility properties. Its solubility is influenced by several factors:

  • Polarity: The presence of the nitrophenyl and carbamoyl functional groups contributes to the overall polarity of the molecule, which typically enhances solubility in polar solvents such as water.
  • Ionization: As a sodium salt, it is expected to dissolve readily in aqueous solutions due to the ability of sodium ions to dissociate in solution, leading to increased solvation of the organic moiety.
  • Temperature: Like many salts, solubility may increase with higher temperatures. Hence, heating a solution could lead to greater dissolution rates.
  • pH Dependence: The solubility of this compound can be affected by the pH of the solution, as it may alter the ionization state of functional groups present within the structure.

Overall, good solubility in water is anticipated, owing to the ionic nature of the sodium salt and the polar characteristics of the carbamoyl and nitrophenyl groups. Additionally, the ability to form hydrogen bonds could facilitate interactions with water molecules, promoting dissolution.

In conclusion, the solubility of sodium 3-[(4-nitrophenyl)carbamoylamino]propanoate reflects a balance of its functional groups and ionic nature, highlighting the importance of understanding these interactions to predict behavior in various environments.

Interesting facts

Interesting Facts about Sodium 3-[(4-Nitrophenyl)carbamoylamino]propanoate

Sodium 3-[(4-nitrophenyl)carbamoylamino]propanoate is a fascinating compound that belongs to the family of amino acid derivatives. Here are some intriguing insights into its structure and applications:

  • Amino Acid Derivative: This compound is an amino acid derivative, specifically related to propanoic acid, which is a fundamental building block for proteins in living organisms.
  • Functional Groups: The molecule features multiple functional groups such as the nitrophenyl group and carboxylic acid, which can influence its reactivity and interaction with biological systems.
  • Biological Significance: Compounds like this are often utilized in biochemical research. They may serve as intermediates in the synthesis of pharmaceuticals or as enzyme inhibitors that can modulate metabolic pathways.
  • Analytical Interest: The presence of the nitrophenyl group makes it a candidate for various analytical assays, including spectrophotometry, where the characteristic absorbance can be used for quantification.
  • Environmental Impact: As with many nitro compounds, there is ongoing research into the environmental impact of its derivatives, particularly concerning their stability and potential toxicological effects.

In the words of a notable chemist, "Each molecule tells a story; understanding its composition allows us to unlock the secrets of chemical interactions and biological functions." This collection of qualities merges the challenges and opportunities present in the study of sodium 3-[(4-nitrophenyl)carbamoylamino]propanoate, making it a worthwhile subject of academic inquiry.


Synonyms
Suosan
140-46-5
p-Nitrophenylcarbamidopropionic acid sodium salt
1-(2-Carboxyethyl)-3-(p-nitrophenyl)urea sodium salt
N-(p-Nitrophenylcarbamoyl)-beta-alanine sodium salt
N-(p-Nitrophenyl)-N'-(beta-carboxyethyl)urea sodium salt
N-(((4-Nitrophenyl)amino)carbonyl)-beta-alanine monosodium salt
6V7T3M79X3
beta-ALANINE, N-((p-NITROPHENYL)CARBAMOYL)-, SODIUM SALT
beta-Alanine, N-(((4-nitrophenyl)amino)carbonyl)-, monosodium salt
sodium;3-[(4-nitrophenyl)carbamoylamino]propanoate
UNII-6V7T3M79X3
AKOS030241498
Q307423
SODIUM .BETA.-(3-(P-NITROPHENYL)UREIDO)PROPIONATE
N-(P-NITROPHENYLCARBAMOYL)-.BETA.-ALANINE SODIUM SALT
.BETA.-ALANINE, N-((P-NITROPHENYL)CARBAMOYL)-, SODIUM SALT
N-(P-NITROPHENYL)-N-(.BETA.-CARBOXYETHYL)UREA SODIUM SALT
beta-Alanine, N-(((4-nitrophenyl)amino)carbonyl)-, monosodium salt (9CI)
.BETA.-ALANINE, N-(((4-NITROPHENYL)AMINO)CARBONYL)-, MONOSODIUM SALT
.BETA.-ALANINE, N-(((4-NITROPHENYL)AMINO)CARBONYL)-, SODIUM SALT (1:1)