Skip to main content

Nitrofurantoin

ADVERTISEMENT
Identification
Molecular formula
C8H6N4O5Na
CAS number
67-20-9
IUPAC name
sodium;3-[[5-(4-nitrophenyl)-2-furyl]methyleneamino]-2-oxo-4H-imidazol-5-olate
State
State

At room temperature, nitrofurantoin is typically found as a solid.

Melting point (Celsius)
272.00
Melting point (Kelvin)
545.15
Boiling point (Celsius)
378.50
Boiling point (Kelvin)
651.65
General information
Molecular weight
238.16g/mol
Molar mass
238.1570g/mol
Density
1.6100g/cm3
Appearence

Nitrofurantoin is an orange-yellow crystalline compound. It is insoluble in water and ether, but slightly soluble in dimethylformamide.

Comment on solubility

Solubility of Sodium 3-[[5-(4-nitrophenyl)-2-furyl]methyleneamino]-2-oxo-4H-imidazol-5-olate

The solubility of sodium 3-[[5-(4-nitrophenyl)-2-furyl]methyleneamino]-2-oxo-4H-imidazol-5-olate can be a fascinating subject due to its unique chemical structure. Understanding its solubility characteristics is essential for various applications. Here are some key points to consider:

  • Nature of the Compound: This compound has functional groups that can interact with solvents, influencing its solubility properties.
  • Polar vs. Non-Polar: Sodium salts typically exhibit higher solubility in polar solvents such as water, due to the ionic nature of the sodium ion.
  • pH Influence: The imidazole ring can be affected by pH changes, potentially altering its solubility depending on the acidity or basicity of the solution.
  • Solvent Choice: To assess solubility effectively, using different solvents can yield varying results. Common solvents to consider include:
    • Water
    • Dimethyl sulfoxide (DMSO)
    • Acetone

As a general observation, compounds with nitrophenyl and furyl groups, like sodium 3-[[5-(4-nitrophenyl)-2-furyl]methyleneamino]-2-oxo-4H-imidazol-5-olate, might display interesting solubility behavior due to their structural complexity. Understanding these solubility aspects can enhance the application potential of the compound in fields such as pharmaceuticals and materials science.

Interesting facts

Interesting Facts about Sodium 3-[[5-(4-nitrophenyl)-2-furyl]methyleneamino]-2-oxo-4H-imidazol-5-olate

Sodium 3-[[5-(4-nitrophenyl)-2-furyl]methyleneamino]-2-oxo-4H-imidazol-5-olate is a fascinating compound that combines organic and inorganic chemistry, showcasing the intricate relationships between various functional groups. Here are some engaging insights about this compound:

  • Unique Structure: This compound features an imidazole ring, which is known for its role in various biological systems, including as a component of the amino acid histidine and many pharmaceuticals.
  • Versatile Applications: Due to its complex structure, this compound may find applications in fields such as medicinal chemistry, agrochemicals, and potentially as a catalyst in organic reactions.
  • Color and Activity: The presence of a nitrophenyl group imparts interesting reactivity and potential color properties, often utilized in dye chemistry and as markers in biological systems.
  • Biological Relevance: Compounds resembling this structure can exhibit significant biological activity. For instance, derivatives of imidazoles have been known to demonstrate anti-fungal and anti-bacterial properties.
  • Pharmacophore Potential: The specific arrangement of atoms in this compound could serve as a potential pharmacophore, meaning it could be a key to designing new drugs targeting specific biological pathways.

Given its intriguing structure and potential applications, sodium 3-[[5-(4-nitrophenyl)-2-furyl]methyleneamino]-2-oxo-4H-imidazol-5-olate represents an exciting area for further research, emphasizing the ongoing importance of interdisciplinary approaches in modern chemistry.

Synonyms
Dantrolene Na
SCHEMBL40892
CHEMBL1725283
SCHEMBL30646901
HMS2231K09
HMS3259L11
HMS3369A09
NC00644
PD003036
NS00076310
Q27106333
2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]- sodium salt (1:1)