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Iohexol

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Identification
Molecular formula
C19H26I3N3NaO9
CAS number
66108-95-0
IUPAC name
sodium;3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoate
State
State

At room temperature, Iohexol is typically in a solid state when isolated as a compound. However, it is commonly used in solution for medical applications as a contrast agent due to its high solubility in water.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
406.50
Boiling point (Kelvin)
679.65
General information
Molecular weight
821.14g/mol
Molar mass
821.1350g/mol
Density
2.1000g/cm3
Appearence

Iohexol is a white to off-white crystalline powder. It may appear as a very fine crystalline solid and is often used in solution as a contrast agent.

Comment on solubility

Solubility of Sodium 3-Acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoate

The solubility of sodium 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoate is influenced by several factors due to its complex structure. Generally, this compound is known to exhibit varying solubility depending on the solvent. Here are some key points regarding its solubility:

  • Water Solubility: The presence of the sodium ion and the acetamido group may enhance the solubility of this compound in polar solvents such as water.
  • Organic Solvents: Conversely, the large molecular structure with multiple iodine atoms can lead to lower solubility in non-polar organic solvents.
  • Temperature Effects: Solubility can increase with temperature; thus, higher temperatures might help dissolve the compound more effectively.
  • pH Sensitivity: The solubility can also be affected by the pH of the solution, as it could influence the ionization of the acetamido and carbamoyl groups.

As a general guideline, it is essential to evaluate the specific solubility conditions when working with this compound. Always conduct thorough solubility tests under various conditions to achieve optimal results.

Interesting facts

Interesting Facts about Sodium 3-Acetamido-2,4,6-Triiodo-5-(Methylcarbamoyl)benzoate

This complex compound, known as sodium 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoate, is of significant interest in the field of chemistry due to its multifaceted applications and unique structure. Here are some riveting aspects of this compound:

  • Pharmaceutical Relevance: This compound is primarily known for its use in medical imaging techniques, particularly due to its iodine content, which enhances contrast in X-ray and CT imaging. The tri-iodo substitution plays a critical role in its efficacy as a contrast agent.
  • Molecular Architecture: The compound features a complex benzene ring substituted with three iodine atoms and functional groups, showcasing how different substituents can influence the compound's reactivity and interaction with biological systems.
  • Active Ingredients: The acetamido and methylcarbamoyl groups contribute to its activity as a molecular agent. These functional groups may enhance the solubility, stability, and bioavailability of the compound in therapeutic applications.
  • Synthetic Pathways: Chemists often explore various synthetic routes to obtain this compound, and investigating these synthesis methods can reveal valuable information about reaction conditions and mechanistic pathways.
  • Research Potential: Due to its structural complexity and therapeutic applications, this compound is a subject of research in the development of new imaging agents and drug formulations, representing a fascinating intersection of medicinal chemistry and material science.

Overall, the exploration of sodium 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoate not only underscores the beauty of chemical complexity but also highlights its pivotal role in advancing medical technologies.