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Roxarsone

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Identification
Molecular formula
C8H8AsNO6Na
CAS number
121-19-7
IUPAC name
sodium;(3-acetamidophenyl)-hydroxy-arsinate
State
State

Roxarsone is typically a solid at room temperature. It is stable under normal conditions and does not easily decompose.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
208.00
Boiling point (Kelvin)
481.15
General information
Molecular weight
263.06g/mol
Molar mass
263.0620g/mol
Density
1.7300g/cm3
Appearence

Roxarsone appears as a white to off-white crystalline solid. It is typically seen in powder form and is known for being sparingly soluble in water.

Comment on solubility

Solubility Characteristics of Sodium (3-Acetamidophenyl)-Hydroxy-Arsinate

The solubility of sodium (3-acetamidophenyl)-hydroxy-arsinate, often referred to as a derivative of arsinate compounds, is influenced by a variety of factors. Understanding these can help in predicting its behavior in different environments:

  • Solvent Type: The compound is expected to be more soluble in polar solvents due to its ionic sodium portion.
  • Temperature Effects: As a general rule, solubility increases with temperature—a principle that typically applies to many ionic compounds.
  • pH Sensitivity: Changes in pH can significantly impact solubility, especially for compounds containing functional groups that can ionize or associate with hydrogen ions.
  • Complexation: The presence of other ions or complexing agents in solution may affect the solubility of this compound by forming soluble complexes.

Generally, sodium (3-acetamidophenyl)-hydroxy-arsinate is considered to have variable solubility, which can be summarized in the following quote:

"Solubility is not just about the sum of molecular interactions; it is a complex interplay of environmental factors."

In conclusion, while this compound has potential solubility in aqueous environments, the specifics would need experimental validation to determine its exact solubility profile under various conditions.

Interesting facts

Interesting Facts about Sodium (3-Acetamidophenyl) Hydroxy-Arsinate

Sodium (3-acetamidophenyl) hydroxy-arsinate is a fascinating chemical compound that combines elements of both organic chemistry and inorganic chemistry. This compound is part of a group of arsenic-containing compounds used in various applications, particularly in the field of medicinal chemistry. Here are some noteworthy facts:

  • Biological Relevance: Compounds like sodium (3-acetamidophenyl) hydroxy-arsinate have shown potential in pharmacological studies, especially for their antitumor properties. Research into arsenic-containing drugs has opened up new avenues for cancer treatments.
  • Mechanism of Action: The mechanism by which this compound exerts its biological effects is of great interest to scientists. Typically, such compounds can interact with cellular pathways, leading to apoptosis in cancer cells.
  • Functional Group Significance: The presence of the acetamidophenyl group suggests that this compound may also exhibit interesting physical and chemical properties, which can be tailored for specific applications in drug development.
  • Environmental Considerations: Researchers are also looking into the environmental impacts and safety profiles of arsenic-containing compounds. With arsenic being a toxic element, it’s crucial to study its implications for both human health and environmental sustainability.
  • Regulation and Safety: The compound falls under close scrutiny due to the toxic nature of arsenic. Understanding its pharmacokinetics and toxicology is essential for determining its feasibility in clinical settings.

As a compound at the intersection of health and safety, sodium (3-acetamidophenyl) hydroxy-arsinate represents the intricate balance chemists must maintain between developing beneficial therapies and ensuring public safety. Its study invites curiosity about not only its chemical properties but also its potential to impact medical science.