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Ceftriaxone

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Identification
Molecular formula
C18H16N8Na2O7S3
CAS number
104376-79-6
IUPAC name
sodium;3-(acetoxymethyl)-7-[[2-(diethylcarbamoylsulfanyl)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
State
State

Ceftriaxone is typically found as a solid at room temperature. It is commonly processed into sterile powders for reconstitution before drug administration.

Melting point (Celsius)
295.00
Melting point (Kelvin)
568.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
554.58g/mol
Molar mass
554.5800g/mol
Density
1.7950g/cm3
Appearence

Ceftriaxone is a pale yellow to yellow crystalline powder. It is soluble in water, sparingly soluble in methanol, and very slightly soluble in ethanol. When dissolved, it typically forms a clear solution.

Comment on solubility

Solubility of Sodium; 3-(Acetoxymethyl)-7-[[2-(Diethylcarbamoylsulfanyl)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

The solubility of sodium; 3-(acetoxymethyl)-7-[[2-(diethylcarbamoylsulfanyl)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is influenced by several factors, notably its chemical structure and ionic composition. Here are some key points to consider:

  • Ionic Nature: Being a sodium compound, it exhibits enhanced solubility in polar solvents, particularly water, due to the presence of the sodium ion which facilitates interaction with water molecules.
  • Functional Groups: The compound contains functional groups such as carboxylate and acetoxy, which can lead to further solubility enhancement through hydrogen bonding with solvents.
  • Overall Structure: The bicyclic structure may influence the solubility, where steric hindrance or hydrophobic regions can play a role in interactions with water.
  • Temperature and pH: The solubility can be affected by environmental conditions, such as temperature or pH, making it essential for applications that require precise solubility control.

In summary, the solubility characteristics of this compound highlight the intricate behaviors dictated by its structural attributes. When considering usage in various chemical processes or formulations, thorough testing under relevant conditions is recommended for accurate assessments of solubility.

Interesting facts

Exciting Facts About Sodium 3-(Acetoxymethyl)-7-[[2-(Diethylcarbamoylsulfanyl)acetyl]amino]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]oct-2-Ene-2-Carboxylate

This compound, though it may seem complex at first glance, is a fascinating example of organic chemistry's breadth and depth. Here are several intriguing aspects to consider:

  • Structural Complexity: The compound features a bicyclic structure, which is not only interesting from a synthetic perspective but also impacts its biological activity. The unique bicyclic arrangement contributes to its three-dimensional shape, crucial for interactions with biological molecules.
  • Functional Groups: This compound has multiple functional groups, including acetoxymethyl and diethylcarbamoylsulfanyl, which can influence its reactivity and solubility. These groups may also play significant roles in its pharmacological properties.
  • Potential Biological Activity: Compounds containing sulfur and nitrogen in their structures have been shown to exhibit various biological activities. This raises potential for its application in drug development or as a biologically active agent.
  • Applications: Understanding the properties of such compounds can lead to their utilization in medicinal chemistry, particularly for designing new drugs or therapeutic agents that target specific diseases.
  • Chemical Versatility: The ability to modify and swap out functional groups allows chemists to tailor the molecule for desired properties, making it a valuable tool in synthetic chemistry.

In the world of chemical research, compounds like sodium 3-(acetoxymethyl)-7-[[2-(diethylcarbamoylsulfanyl)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate remind us of the intricacies of molecular design and highlight the potential for innovation in the field!