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Cefuroxime Sodium

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Identification
Molecular formula
C16H15N4NaO8S
CAS number
56238-63-2
IUPAC name
sodium;3-(acetoxymethyl)-8-oxo-7-[[2-(4-pyridylsulfanyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
State
State

At room temperature, cefuroxime sodium is in a solid state, specifically a crystalline powder.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
-1.00
General information
Molecular weight
446.37g/mol
Molar mass
446.3800g/mol
Density
1.7500g/cm3
Appearence

Cefuroxime sodium is typically a white to off-white crystalline powder. It is often used for medicinal purposes and may appear in a lyophilized form for injections.

Comment on solubility

Solubility of Sodium 3-(Acetoxymethyl)-8-oxo-7-[[2-(4-pyridylsulfanyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

The solubility of sodium 3-(acetoxymethyl)-8-oxo-7-[[2-(4-pyridylsulfanyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is an intriguing aspect of its chemical behavior. This compound, characterized by its complex structure, exhibits unique solubility properties influenced by its various functional groups.

Factors Influencing Solubility

  • Polarity: The presence of polar functional groups, especially the sulfonamide and carboxylate, enhances solubility in polar solvents like water.
  • Ionic Nature: As a sodium salt, it is expected to dissolve well in aqueous environments due to ion-dipole interactions with water molecules.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water can significantly increase solubility. The acetoxymethyl and carboxylate groups contribute to this interaction.

In general, compounds with similar structures are often soluble in water, and this compound is likely no exception. Quotes such as "Like dissolves like" can be applied here, indicating that due to its ionic and polar characteristics, the compound favors solubility in polar solvents.

Overall, sodium 3-(acetoxymethyl)-8-oxo-7-[[2-(4-pyridylsulfanyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is expected to have considerable solubility in water, enhancing its utility in various applications.

Interesting facts

Interesting Facts about Sodium; 3-(Acetoxymethyl)-8-Oxo-7-[[2-(4-Pyridylsulfanyl)acetyl]amino]-5-Thia-1-Azabicyclo[4.2.0]oct-2-Ene-2-Carboxylate

This fascinating compound is a member of a diverse class of organic molecules known for their biochemical significance. Here are some interesting points to consider:

  • Multifunctional Potential: The structure of this compound features multiple functional groups that could potentially lead to various biological activities, making it a candidate for drug development.
  • Pyridylsulfanyl Moiety: The presence of the 4-pyridylsulfanyl group can influence the compound's ability to interact with biological targets, suggesting possible roles in medicinal chemistry.
  • Thia-azabicyclic Structure: The bicyclic framework provides structural rigidity that can be crucial in the design of pharmaceuticals, often contributing to the compound's potency and selectivity in biological systems.
  • Acetoxymethyl Substituent: The acetoxymethyl group may enhance solubility and bioavailability, which is critical for therapeutic efficacy.
  • Research Applications: Compounds like this one are often utilized in research, particularly in studies involving enzyme inhibition or antibacterial properties.

Understanding and exploring such complex structures not only aids in the development of new therapeutics but also enhances our knowledge of chemical interactions in biological systems. As one might say in the lab, "Every molecule has a story to tell!"

In conclusion, the intricate design and unique functionalities of sodium; 3-(acetoxymethyl)-8-oxo-7-[[2-(4-pyridylsulfanyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate make it a remarkable subject of study in the realms of organic chemistry and pharmacology.