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Ceftizoxime

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Identification
Molecular formula
C13H12N4NaO5S2
CAS number
68401-81-0
IUPAC name
sodium;3,3-dimethyl-6-[(5-methyl-3-phenyl-isothiazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
State
State
Ceftizoxime sodium is typically supplied as a solid crystalline powder. When prepared for administration as an injection, it is dissolved in a sterile solvent to form a solution.
Melting point (Celsius)
142.00
Melting point (Kelvin)
415.00
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.00
General information
Molecular weight
399.38g/mol
Molar mass
399.4530g/mol
Density
1.6700g/cm3
Appearence
Ceftizoxime is usually encountered as a white to off-white crystalline powder. It may be slightly hydroscopic in nature. As a pharmaceutical compound, it is often formulated in combination with excipients for stability and delivery.
Comment on solubility

Solubility Characteristics of Sodium 3,3-Dimethyl-6-[(5-Methyl-3-Phenyl-Isothiazole-4-Carbonyl)Amino]-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate

The solubility of sodium 3,3-dimethyl-6-[(5-methyl-3-phenyl-isothiazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate is a critical property to consider in various applications. Here are some key factors affecting its solubility:

  • Polarity: Due to the presence of both hydrophilic and hydrophobic groups, this compound exhibits a degree of polarity, which can influence its interaction with solvents.
  • Ionic Nature: As a sodium salt, it is generally more soluble in polar solvents like water compared to non-polar solvents. This can lead to significant solubility when the ionic bond is easily broken.
  • pH Dependence: The solubility can vary with pH, especially if the compound has ionizable functional groups. At certain pH levels, enhanced solubility could be observed.
  • Temperature Influence: Increased temperatures often enhance the solubility of organic compounds. Thus, solubility measurements should consider temperature variations.

In summary, while sodium 3,3-dimethyl-6-[(5-methyl-3-phenyl-isothiazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate likely exhibits reasonable solubility in polar solvents, the exact solubility profile may depend on specific environmental conditions such as polarity, pH, and temperature.

Interesting facts

Interesting Facts about Sodium 3,3-Dimethyl-6-[(5-Methyl-3-Phenyl-Isothiazole-4-Carbonyl)amino]-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]heptane-2-Carboxylate

This intriguing compound is notable for its unique structural configuration, reflecting its classification among advanced chemical compounds. Here are several fascinating aspects:

  • Complex Structure: The compound incorporates a bicyclic system and features a thiazole moiety, which contributes to its potential pharmacological properties.
  • Potential Therapeutic Properties: Compounds with isothiazole rings are often studied for their biological activities. This could indicate possible applications in medicinal chemistry, especially in developing novel drugs.
  • Versatile Functional Groups: The presence of diverse functional groups, including carboxylate and carbonyl units, enhances the compound's reactivity and opens avenues for further chemical transformations.
  • Chirality: Given its structural complexity, this compound may exhibit chirality, which can lead to different biological effects from enantiomers. This factor is essential in drug design, as enantiomeric forms can have varying efficacy and safety profiles.

In the realm of scientific research, this compound emphasizes the importance of structural diversity in the development of new materials and pharmaceuticals. As noted by many chemists, "the beauty of chemistry lies in its complexity and the promises it holds for future innovations."

Moreover, the intricate nature of this compound encourages ongoing studies to unravel its full potential, which remains an exciting frontier for researchers in organic chemistry and drug discovery.