Cloxacillin sodium | Solubility of Things

Identification

Molecular formula

C₁₉H₁₇ClN₃NaO₅S

CAS number

7081-44-9

IUPAC name

sodium;3,3-dimethyl-6-[(5-methyl-3-phenyl-isoxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

State

Cloxacillin sodium is typically available in solid form, either as a powder or as crystalline solids at room temperature. It is hygroscopic and should be stored in an airtight container to prevent absorption of moisture.

Melting point (Celsius)

178.00

Melting point (Kelvin)

451.15

Boiling point (Celsius)

0.00

Boiling point (Kelvin)

0.00

General information

Molecular weight

457.86g/mol

Molar mass

457.9100g/mol

Density

1.5600g/cm³

Appearence

Cloxacillin sodium appears as a white to off-white crystalline powder. It is typically odorless or may have a faint odor characteristic of the penicillin analogs.

Comment on solubility

Solubility Overview

The compound sodium 3,3-dimethyl-6-[(5-methyl-3-phenyl-isoxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate can present unique solubility characteristics due to its complex chemical structure. Understanding its solubility is crucial for various applications. Here are some key points to consider:

Polarity: The presence of polar functional groups, such as the carboxylate and amide components, suggests that the compound may exhibit higher solubility in polar solvents, like water.
Hydrophobic Interactions: The aromatic phenyl ring and aliphatic chains may impart some hydrophobic nature, potentially decreasing solubility in highly polar solvents.
pH Dependence: The solubility might vary with changes in pH, considering the carboxylate group can ionize, impacting the overall solubility in aqueous solutions.
Concentration Effects: As with many organic compounds, the solubility may also be affected by concentration, temperature, and the presence of other solutes.

In conclusion, the solubility of sodium 3,3-dimethyl-6-[(5-methyl-3-phenyl-isoxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate is a multifaceted topic, and it would be beneficial to conduct detailed experimental studies for precise insights. Overall, the interplay of polar and non-polar characteristics makes it an intriguing subject for further research.

Interesting facts

Interesting Facts about Sodium 3,3-Dimethyl-6-[(5-Methyl-3-Phenyl-Isoxazole-4-Carbonyl)Amino]-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate

This fascinating compound, known for its complex structure, showcases the beauty of organic chemistry and medicinal applications. Below are some intriguing aspects of this compound:

Structural Complexity: The unique bicyclic structure of this compound provides a biological context that could lead to significant pharmaceutical properties. Its ability to embed various functional groups makes it a potent candidate for drug development.
Isoxazole Derivative: The presence of the isoxazole moiety suggests it's involved in several biological activities, making this compound particularly interesting in the field of medicinal chemistry.
Potential Applications: Compounds like this are often explored for their potential use as therapeutic agents, ranging from anti-inflammatory to anti-cancer properties. Researchers continuously investigate how structural modifications can enhance biological efficacy.
Importance of Sodium: The sodium component in this compound plays a crucial role in its solubility and bioavailability, which significantly influences its pharmacodynamics and pharmacokinetics.
Historical Context: The development of compounds like this represents the advanced intersection of synthetic chemistry and biological application, underscoring decades of research into redox-active molecules.

In conclusion, sodium 3,3-dimethyl-6-[(5-methyl-3-phenyl-isoxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate exemplifies the innovative possibilities within molecular design and highlights ongoing efforts in the quest for new therapeutics.