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Cortisone acetate sodium salt

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Identification
Molecular formula
C24H31NaO7
CAS number
NA
IUPAC name
sodium;4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoate
State
State
The compound is typically in a solid state at room temperature, appearing as a crystalline powder with a fine structure suitable for laboratory or pharmaceutical applications. It is stable under standard conditions.
Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
470.00
Boiling point (Kelvin)
743.15
General information
Molecular weight
474.56g/mol
Molar mass
474.5580g/mol
Density
1.2400g/cm3
Appearence

The compound is typically a white to off-white crystalline powder. It may exhibit slight hygroscopic properties, depending on the humidity of the environment. It is usually odorless and should be stored in a sealed container away from light and moisture to prevent degradation.

Comment on solubility

Solubility of sodium 4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoate

The solubility of sodium 4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoate can be influenced by various factors, given its complex structure. Here are key points to consider:

  • Polarity: Compounds with polar functional groups typically possess higher solubility in polar solvents. The presence of hydroxyl (-OH) and carboxylate (-COO-) groups suggests good solubility in water.
  • Underlying Structure: The bulkiness of the steroid-derived portion of the molecule may hinder solubility in some organic solvents, despite the presence of smaller polar groups.
  • pH Sensitivity: The solubility may vary with changes in pH, as the deprotonation of acidic groups can enhance solubility in basic conditions.

While limited concrete data may exist on this specific compound's solubility, it is reasonable to predict:

  1. Prominent solubility in aqueous environments due to ionic interactions.
  2. Potential challenges in non-polar solvents linked to its steroid-like structure.
  3. A variable solubility depending on the presence of co-solvents or additives that could stabilize solubility.

Ultimately, empirical testing would provide the most accurate picture of solubility characteristics for this intriguing compound, revealing its utility in various applications.

Interesting facts

Interesting Facts about Sodium 4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoate

This complex compound is a derivative of a natural steroid framework, which offers a fascinating glimpse into the world of chemical synthesis and biological activity. Below are some remarkable facts that highlight its significance:

  • Biological Relevance: This compound relates to steroid metabolism and can have applications in pharmacology, particularly in the development of drugs targeting hormonal pathways.
  • Synthetic Versatility: The intricate structure demonstrates the potential for synthesizing compounds with modified steroidal backbones, showcasing how organic chemistry can be used to explore the therapeutic possibilities of steroids.
  • Functional Groups: With multiple hydroxyl groups and oxo-functionalities, this compound exhibits a wide range of chemical reactivity, making it suitable for various chemical transformations.
  • Isomerism: The presence of chiral centers indicates that this compound may exist in multiple stereoisomeric forms, each possibly possessing distinct biological properties.
  • Mechanism Exploration: Researchers are intrigued by how the various functional groups interact at the molecular level and their implications on the compound’s efficacy in biological systems.
  • Research Potential: Given its structural diversity, the compound presents extensive opportunities for medicinal chemistry research, with potential implications in treating hormone-related diseases, certain cancers, and other health issues.

Thus, the sodium salt form of this compound invites a deep exploration into its applications and syntheses in the realm of medicinal chemistry. Its structural complexity not only makes it a subject of study but also a powerful tool in exploring the depths of biological interactions.