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Dexamethasone sodium phosphate

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Identification
Molecular formula
C22H28FNaO8
CAS number
55203-24-2
IUPAC name
sodium;4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoate
State
State

At room temperature, dexamethasone sodium phosphate is a solid substance. It is stable under normal conditions and is typically used in its crystalline form for pharmaceutical purposes.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
472.44g/mol
Molar mass
472.4350g/mol
Density
1.3000g/cm3
Appearence

Dexamethasone sodium phosphate appears as a white or almost white crystalline powder.

Comment on solubility

Solubility of Sodium 4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoate

The solubility of sodium 4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoate can be understood through several key factors:

  • Sodium Salt Formation: As a sodium salt, this compound is likely to exhibit greater solubility in polar solvents, particularly water, compared to its un-ionized form. Sodium ions can facilitate interactions with water molecules.
  • Structural Considerations: The complex organic backbone, featuring multiple hydroxyl and carbonyl groups, may enhance solubility through hydrogen bonding with solvent molecules, particularly in aqueous environments.
  • Concentration Effects: The solubility can vary significantly with temperature; generally, an increase in temperature may lead to increased solubility for many sodium salts.

In summary, while the specific solubility of this compound in water may require empirical testing to quantify, it is expected to show decent solubility due to its ionic nature and the presence of functional groups that promote solvation. As noted, "the balance between hydrophilicity and hydrophobicity will play a crucial role" in its overall solubility profile.

Interesting facts

Interesting Facts about the Compound Sodium 4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoate

This compound is a fascinating example of a complex organic molecule that exhibits significant biological activity. Below are some engaging aspects of this compound:

  • Structural Complexity: This compound incorporates a range of functional groups, contributing to its unique chemical behavior. Notably, it includes both an ethoxy group and a butanoate moiety, enhancing its solubility and interaction with biological systems.
  • Biological Significance: Compounds like this one can play crucial roles in various biological processes. They are often studied for their potential therapeutic effects, especially in areas related to hormonal regulation and metabolic pathways.
  • Similarities to Natural Compounds: The structure of this compound resembles natural steroid-like structures, suggesting that it may interact with hormone receptors, which could lead to significant physiological effects.
  • Potential Applications: Due to its complex structure and potential biological activity, this compound may be explored in drug discovery and development. Researchers are particularly interested in compounds that can modulate biological pathways in targeted ways.
  • Research Implications: The compound's intricate structure provides a platform for chemists to explore synthetic modifications, thereby enhancing its biological properties or reducing side effects.

In conclusion, the study of sodium 4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoate not only illustrates the beauty of organic chemistry but also emphasizes the importance of structural diversity in the discovery of pioneering new therapeutics. As we continue to uncover the roles of such compounds, we embrace the potential for significant advancements in medicine and science.