Skip to main content

Fluticasone propionate

ADVERTISEMENT
Identification
Molecular formula
C25H31F3O5S
CAS number
80474-14-2
IUPAC name
sodium;4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate
State
State

At room temperature, fluticasone propionate is in a solid state. It is typically handled in a powdered form for pharmaceutical uses.

Melting point (Celsius)
273.00
Melting point (Kelvin)
546.15
Boiling point (Celsius)
915.00
Boiling point (Kelvin)
1 188.15
General information
Molecular weight
500.57g/mol
Molar mass
500.5740g/mol
Density
1.4400g/cm3
Appearence

Fluticasone propionate is a white to off-white powder. It appears crystalline and pure in form. In its basic formulation, it is devoid of coloration and presents as a solid at room temperature.

Comment on solubility

Solubility of sodium;4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate

The solubility of sodium;4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate is influenced by various factors.

Key solubility features include:

  • Polarity: The presence of hydroxyl groups and other polar functional groups in the compound contributes to its potential solubility in polar solvents such as water.
  • Ionic nature: As a sodium salt, it is likely to dissociate in aqueous solutions, enhancing its solubility compared to its neutral counterparts.
  • Hydrophobic regions: The compound also contains hydrophobic components due to its steroid-like structure, which may limit solubility in non-polar solvents.

Furthermore, the solubility can vary with temperature and the pH of the solution. In aqueous environments, increased temperatures often lead to better solute interaction and enhanced solubility, whereas extreme pH levels might affect ionization and solubility behavior.

In conclusion, while the exact solubility can be varied and context-dependent, understanding its structural features provides insights into its expected behavior in different solvent systems.

Interesting facts

Interesting Facts about Sodium; 4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate

This compound is a fascinating example of a complex organic molecule that showcases the diversity found in chemical structures. It combines various functional groups, highlighting the intricate relationships between structure and biological activity.

Key Features

  • Hormonal Relevance: This compound is related to steroid hormones, which play essential roles in regulating a wide range of physiological processes within organisms.
  • Synthetic Applications: This type of compound can be synthesized using modern organic chemistry techniques, illustrating the remarkable progress in synthetic methodologies.
  • Health Implications: Due to its steroid-like structure, it may have potential therapeutic applications, particularly in the fields of endocrinology and oncology.

The stereochemistry of the molecule is particularly interesting. With multiple chiral centers, the configuration can greatly affect the compound's biological activity. As a chemistry student, understanding such stereochemical elements is crucial, as they determine how the compound interacts with biological systems.

Research Potential

Ongoing research may focus on:

  • Exploring the compound's interaction with steroid receptors.
  • Investigating its effects on metabolism and growth processes.
  • Evaluating its pharmacological properties in various disease models.

As you dive deeper into the study of such compounds, remember the profound impact that molecular structure has on function. Each new compound brings a wealth of information and potential discoveries waiting to be uncovered!