Skip to main content

Chlorambucil Sodium Salt

ADVERTISEMENT
Identification
Molecular formula
C14H18Cl2NO2Na
CAS number
305-03-3
IUPAC name
sodium;4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate
State
State
At room temperature, chlorambucil sodium salt is typically a solid. Due to its hygroscopic nature, care must be taken to prevent exposure to moisture.
Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
475.00
Boiling point (Kelvin)
748.15
General information
Molecular weight
354.68g/mol
Molar mass
354.6790g/mol
Density
1.0800g/cm3
Appearence

Chlorambucil sodium salt usually appears as a white to pale yellow crystalline powder. It is known to be hygroscopic, meaning it can absorb moisture from the air. When pure, it may appear as a solid material that can be easily handled.

Comment on solubility

Solubility of Sodium 4-[4-[Bis(2-chloroethyl)amino]phenyl]butanoate

The solubility of sodium 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate can be quite interesting, especially considering its unique structure. This compound, bearing both hydrophilic and hydrophobic characteristics, may demonstrate varying solubility in different environments. Here are some key points regarding its solubility:

  • Polar Nature: The presence of the sodium ion contributes to the compound's ability to dissolve in polar solvents, particularly water.
  • Hydrophobic Portions: The hydrophobic bis(2-chloroethyl)amino groups may impede solubility in non-polar solvents.
  • pH Dependency: Solubility can also be influenced by the pH of the solution, as the ionization states of the amine groups can change.
  • Temperature Effect: The solubility may increase with temperature, which is a common characteristic of many solid compounds.

Overall, "solubility is the key to understanding a compound's behavior in various applications." Thus, knowing the solubility characteristics of sodium 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate is crucial for its practical use in fields such as pharmaceuticals and chemical engineering.

Interesting facts

Interesting Facts About Sodium; 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate

Sodium; 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate, often hailed for its intriguing chemical properties, belongs to a class of compounds known as amino acid derivatives. Here are some captivating insights:

  • Pharmaceutical Relevance: This compound has shown potential in the field of medicinal chemistry, particularly in anticancer treatments. The bis(2-chloroethyl)amino group is reminiscent of alkylating agents, which play a critical role in chemotherapy.
  • Structure-Activity Relationship: The design of this compound highlights the importance of the side groups on its aromatic rings. Alterations can significantly affect its biological activity, making it a focal point for drug design studies.
  • Chirality Considerations: As a compound derived from a butanoic acid framework, it raises interesting questions regarding chirality and the potential effects of stereoisomers on its efficacy and safety.
  • Mechanism Exploration: Research has delved into its mechanism of action, revealing insights into how it interacts at the molecular level with cancer cell DNA, presenting an avenue for further therapeutic applications.
  • Innovation in Synthesis: The synthesis of this compound exemplifies modern organic chemistry techniques, utilizing methods such as nucleophilic substitution and aromatic substitution, showcasing the evolution of synthetic strategies.

This compound is a prime example of how small structural modifications can lead to significant changes in biological activity, presenting a remarkable opportunity for researchers in the fields of medicinal chemistry and pharmacology. As we continue to explore and study such compounds, they may lead us to groundbreaking discoveries in the quest for effective treatments.