Skip to main content

Sulfacetamide sodium

ADVERTISEMENT
Identification
Molecular formula
C10H11N2NaO3S
CAS number
127-56-0
IUPAC name
sodium;(4-aminophenyl)sulfonyl-(4-methylpyrimidin-2-yl)azanide
State
State
At room temperature, sulfacetamide sodium is typically found in a solid state as a crystalline powder.
Melting point (Celsius)
202.00
Melting point (Kelvin)
475.15
Boiling point (Celsius)
355.00
Boiling point (Kelvin)
628.15
General information
Molecular weight
254.25g/mol
Molar mass
254.2530g/mol
Density
1.4400g/cm3
Appearence
Sulfacetamide sodium typically appears as a white, crystalline powder. It is relatively odorless and is soluble in water, making it easy to formulate for various pharmaceutical applications.
Comment on solubility

Solubility of Sodium (4-Aminophenyl) Sulfonyl (4-Methylpyrimidin-2-Yl) Azanide

This compound exhibits unique solubility characteristics due to its molecular structure and the presence of both sodium and organic functional groups. When analyzing solubility, several key factors come into play:

  • Ionic Nature: The presence of sodium typically suggests that the compound is likely to be soluble in polar solvents, especially water, due to ionic interactions.
  • Hydrogen Bonding: The amino group (-NH2) and sulfonyl group (-SO2-) can form hydrogen bonds with solvents, enhancing solubility.
  • Hydrophobic Interactions: The pyrimidine ring adds some hydrophobic character, which can hinder solubility in highly polar environments.

In summary, the solubility of sodium (4-aminophenyl) sulfonyl (4-methylpyrimidin-2-yl) azanide is expected to be:

  • High in water due to the ionic nature from sodium.
  • Variable in organic solvents, depending on their polarity.
  • Enhanced when exposed to hydrogen-bonding solvents like alcohols.

Understanding these properties is vital for applications involving this compound, as solubility can profoundly affect its reactivity and biological interactions.

Interesting facts

Interesting Facts About Sodium (4-Aminophenyl) Sulfonyl-(4-Methylpyrimidin-2-yl) Azanide

This compound represents a fascinating intersection of organic chemistry and pharmaceutical applications. As a sodium salt, it showcases the characteristic reactivity and solubility properties associated with sodium derivatives.

Key Highlights:

  • Targeting Mechanism: This compound may play a role in medicinal chemistry, potentially serving as an important building block in the synthesis of drugs targeting specific biological pathways.
  • Structural Diversity: The presence of the 4-aminophenyl and 4-methylpyrimidin-2-yl groups indicates a structural variety that may offer unique interactions in biological systems.
  • Functional Groups: With amino, sulfonyl, and azanide moieties, this compound is rich in functional groups that can participate in various chemical reactions, making it a versatile candidate for further chemical investigations.
  • Research Interest: Compounds like this are often studied for their inhibitory effects on certain enzymes, possibly leading to advancements in drug development for various diseases.

As noted in the literature, "The incorporation of *sulfonamide* structure significantly enhances antibacterial activity", illustrating the medicinal potential embedded within the design of this compound.

This sodium salt not only boosts its solubility compared to its acid form but also facilitates easier administration in pharmaceutical formulations. As research continues, compounds like sodium (4-aminophenyl) sulfonyl-(4-methylpyrimidin-2-yl) azanide will likely be at the forefront of innovative therapeutic developments.