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Sulfamethazine sodium

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Identification
Molecular formula
C12H13N4NaO2S
CAS number
1981-58-4
IUPAC name
sodium;(4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide
State
State

At room temperature, sulfamethazine sodium exists in a solid state. It is commonly used in its sodium salt form to enhance aqueous solubility, improving the compound's effectiveness in pharmaceutical applications.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
517.40
Boiling point (Kelvin)
790.55
General information
Molecular weight
278.31g/mol
Molar mass
278.3340g/mol
Density
1.4500g/cm3
Appearence

Sulfamethazine sodium is typically marketed as a white to slightly yellowish crystalline powder. It is crystalline in nature and is readily soluble in water, providing a clear solution when dissolved.

Comment on solubility

Solubility of Sodium (4-Aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide

The solubility of sodium (4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide in various solvents is an important characteristic that can influence its use in different applications. This compound displays interesting solubility characteristics based on its chemical structure.

Key Factors Affecting Solubility:

  • Polarity: Since the compound contains a sulfonamide group, it is likely to exhibit polar characteristics, which often enhances solubility in polar solvents such as water.
  • Ionic Nature: The presence of sodium suggests that it may dissociate in solution, aiding its solubility in aqueous environments.
  • Hydrogen Bonding: The amine groups can form hydrogen bonds with solvent molecules, potentially increasing solubility in certain conditions.

In summary, while precise solubility data may vary, one can expect that sodium (4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide will have favorable solubility in water due to its ionic and polar nature. As noted, "the interplay of structure, ionic dissociation, and solvent interactions can result in a range of solubility behaviors." Understanding these behaviors is vital for researchers and chemists working with this compound.

Interesting facts

Interesting Facts about Sodium (4-Aminophenyl) Sulfonyl (4,6-Dimethylpyrimidin-2-yl) Azanide

This compound represents a fascinating intersection of organic chemistry and medicinal applications. With its structure reflecting both amine and sulfonamide groups, it showcases the versatility of synthetic chemistry in creating compounds with potential therapeutic effects. Here are some notable points:

  • Mechanism of Action: Compounds like this one often serve as vital intermediaries in the synthesis of pharmaceuticals, particularly in the development of new anti-microbial agents.
  • Research Applications: The unique combination of the pyrimidine and sulfonyl groups may play roles in biological pathways, making it a subject of research in drug development.
  • Chemical Stability: The stability of sulfonamide compounds is an important feature that contributes to their effectiveness in various applications; they resist hydrolysis under physiological conditions.
  • Impacts on Health: This class of compounds is known for their utility in treating bacterial infections, representing a significant milestone in modern medicine since their discovery in the early 20th century.
  • Structural Diversity: The various functional groups present in sodium (4-aminophenyl) sulfonyl (4,6-dimethylpyrimidin-2-yl) azanide can result in a wide range of biological activities depending on their configuration.

In summary, the chemical structure of this compound not only adds to its significance in synthetic chemistry but also hints at its potential roles in advancements in medicinal chemistry. As researchers continue to unravel the intricate details of such compounds, they may lead to breakthroughs in treating challenging diseases.