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Sulfasalazine

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Identification
Molecular formula
C18H14N4O5S
CAS number
599-79-1
IUPAC name
sodium;(4-aminophenyl)sulfonyl-pyrazin-2-yl-azanide
State
State

At room temperature, Sulfasalazine is a solid, existing typically in a granular or powdered form.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.00
Boiling point (Celsius)
628.90
Boiling point (Kelvin)
902.00
General information
Molecular weight
398.39g/mol
Molar mass
398.3860g/mol
Density
1.4990g/cm3
Appearence

Sulfasalazine is an orange-yellow crystalline powder that is practically odorless. Its appearance is quite distinctive due to its characteristic color, which is typically deeper than many other compounds.

Comment on solubility

Solubility of Sodium (4-Aminophenyl) Sulfonyl-Pyrazin-2-yl-Azanide

The solubility profile of sodium (4-aminophenyl) sulfonyl-pyrazin-2-yl-azanide can be intriguing due to its unique chemical structure. Understanding its solubility characteristics is crucial for applications in pharmaceuticals and other fields.

Factors Affecting Solubility

Several factors play a role in determining the solubility of this compound, including:

  • Nature of the Solvent: The choice of solvent is critical; polar solvents like water may enhance solubility due to the ionic nature of sodium.
  • Temperature: Generally, increasing the temperature tends to increase solubility, but this can vary depending on the specific interactions at play.
  • pH of the Solution: Changes in pH can significantly influence the state of ionization of the compound, affecting its solubility in aqueous environments.

Expected Behavior

Based on its structure, one might consider the following points:

  • The presence of the sulfonyl group provides polar characteristics, which may enhance solubility in certain solvents.
  • The amine functional group is known for forming hydrogen bonds, potentially increasing solubility in polar media.
  • It may exhibit variable solubility, being soluble in some solvents but not in others, leading to the need for experimentation.

In summary, the solubility of sodium (4-aminophenyl) sulfonyl-pyrazin-2-yl-azanide is expected to be influenced by multiple factors, and empirical testing in various solvents would provide a clearer picture of its behavior. Proper understanding can pave the way for enhanced applications in diverse chemical processes.

Interesting facts

Interesting Facts About Sodium (4-Aminophenyl) Sulfonyl Pyrazin-2-yl Azanide

The compound sodium (4-aminophenyl) sulfonyl pyrazin-2-yl azanide is a remarkable chemical that falls under the category of sulfonamides and is associated with various applications in the field of medicinal chemistry. Here are some fascinating points about this compound:

  • Biological Relevance: Compounds like this one often exhibit antibacterial properties, making them valuable in the development of pharmaceuticals aimed at treating infections.
  • Mechanism of Action: The sulfonamide moiety in its structure can inhibit the bacterial synthesis of folic acid, which is crucial for bacterial growth and reproduction, thereby demonstrating its potential as an antimicrobial agent.
  • Research Applications: Due to its unique structural features, this compound is of interest in drug discovery research, particularly in designing new therapeutic agents that can improve efficacy and reduce side effects.
  • Diverse Synthetic Pathways: The synthesis of this chemical can be achieved through various methods, which allows chemists to explore different routes to manipulate its properties for specific applications.
  • Engineering Properties: Understanding the physicochemical properties of this compound can provide insights into its behavior in biological systems, which is vital for developing effective drug formulations.

Overall, sodium (4-aminophenyl) sulfonyl pyrazin-2-yl azanide showcases the intricate relationship between chemical structure and biological activity, allowing researchers to unlock new potential in therapeutic advancements.