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Sodium sulfamate

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Identification
Molecular formula
NaSO2NH2
CAS number
13845-18-6
IUPAC name
sodium;(4-aminophenyl)sulfonylazanide
State
State

At room temperature, sodium sulfamate is a solid. It exists in a stable form under normal conditions and is typically handled as a fine powder or as crystals.

Melting point (Celsius)
350.00
Melting point (Kelvin)
623.20
Boiling point (Celsius)
260.60
Boiling point (Kelvin)
533.80
General information
Molecular weight
137.07g/mol
Molar mass
137.0680g/mol
Density
2.1000g/cm3
Appearence

Sodium sulfamate typically appears as a white, crystalline solid. These crystals are often odorless and highly soluble in water, forming clear solutions.

Comment on solubility

Solubility of Sodium (4-Aminophenyl) Sulfonylazanide

Sodium (4-Aminophenyl) sulfonylazanide, with its intricate structure, shows interesting solubility characteristics that are important for its functionality in various applications. Understanding its solubility is crucial for determining how it interacts with solvents and other substances in chemical processes. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is generally soluble in polar solvents such as water, primarily due to the presence of the sulfonyl group which enhances its ability to interact with polar molecules.
  • Temperature Influence: Solubility can increase with temperature; thus, understanding how temperature affects dissolution is vital for practical applications.
  • pH Sensitivity: The solubility may vary with pH levels, as alterations in acidity can alter the ionization of functional groups, affecting solubility in aqueous environments.

As with many compounds, it is essential to note that “like dissolves like.” Thus, polar compounds like sodium (4-aminophenyl) sulfonylazanide tend to have enhanced solubility in polar solvents. By experimenting with different conditions, one can uncover the most effective formulations for utilizing this compound in chemical processes.

Interesting facts

Interesting Facts about Sodium (4-Aminophenyl)sulfonylazanide

Sodium (4-aminophenyl)sulfonylazanide, commonly known as a sulfonamide, belongs to a class of compounds that have significant implications in both medicinal chemistry and biological research. Here are some notable aspects of this compound:

  • Pharmaceutical Importance: Sulfonamides, including sodium (4-aminophenyl)sulfonylazanide, were among the first broad-spectrum antibiotics. They revolutionized the treatment of bacterial infections in the mid-20th century.
  • Mechanism of Action: This compound acts by inhibiting bacterial synthesis of folic acid, a crucial nutrient for DNA synthesis. This mechanism is shared by many sulfonamide drugs, making them effective against a variety of bacterial pathogens.
  • Applications in Research: Beyond its antibacterial properties, this compound is used in the synthesis of various pharmaceuticals and chemical probes. Its versatility in organic synthesis opens new avenues for research and drug development.
  • Safety and Side Effects: While effective, sulfonamides can have side effects ranging from mild allergic reactions to more severe conditions, such as Stevens-Johnson syndrome. Understanding these risks is crucial in clinical settings.

“Exploring the world of sulfonamides feels like discovering a treasure chest of medicinal chemistry.” This quote embodies the marvel surrounding compounds like sodium (4-aminophenyl)sulfonylazanide, as they bridge the gap between basic research and therapeutic application.

As a part of the sulfonamide family, this compound continues to inspire chemists to develop safer and more effective antibiotics, showcasing the ongoing importance of research in this field.