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Sodium Tiopental

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Identification
Molecular formula
C11H17N2NaO2S
CAS number
71-73-8
IUPAC name
sodium;5-allyl-5-(1-methylbutyl)-4,6-dioxo-1H-pyrimidin-2-olate
State
State

At room temperature, sodium thiopental is typically encountered as a solid. It is highly soluble in water, which makes it convenient for use in solution form as an intravenous anesthetic.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.00
Boiling point (Celsius)
323.00
Boiling point (Kelvin)
596.00
General information
Molecular weight
264.32g/mol
Molar mass
264.3200g/mol
Density
1.0466g/cm3
Appearence

Sodium thiopental typically appears as a white, crystalline powder. It is odorless or may have a slight characteristic odor. The compound can sometimes exhibit a creamy-white or pale cream color due to impurities or variations in manufacturing processes.

Comment on solubility

Solubility of Sodium; 5-allyl-5-(1-methylbutyl)-4,6-dioxo-1H-pyrimidin-2-olate

The solubility of sodium; 5-allyl-5-(1-methylbutyl)-4,6-dioxo-1H-pyrimidin-2-olate can be influenced by several key factors. Understanding these factors is critical for effectively utilizing this compound in various applications.

  • Polarity of the Compound: The presence of polar functional groups such as –C=O can enhance solubility in polar solvents, while non-polar sections may hinder it.
  • pH of the Solution: As a salt, the compound’s solubility may be affected by the pH, influencing its ionization and, consequently, its solubility.
  • Temperature: Generally, as temperature increases, solubility also tends to increase. However, this can vary depending on the compound.
  • Solvent Type: This compound is likely to be more soluble in polar aprotic solvents (e.g., DMF or DMSO) than in non-polar solvents (e.g., hexane).

To quote the principle of solubility:

"Like dissolves like." This means that polar solvents are best at dissolving polar substances, whereas non-polar solvents are suited for non-polar substances.

In summary, while detailed solubility data may be scarce for sodium; 5-allyl-5-(1-methylbutyl)-4,6-dioxo-1H-pyrimidin-2-olate, careful consideration of its molecular structure and the surrounding conditions can provide insights into its expected solubility behavior.

Interesting facts

Interesting Facts about Sodium; 5-allyl-5-(1-methylbutyl)-4,6-dioxo-1H-pyrimidin-2-olate

This compound, featuring a unique structure, plays a significant role in various chemical applications. Here are some intriguing insights:

  • Biological Relevance: Compounds like this one can mimic important biological molecules, making them valuable in medicinal chemistry. Their structural resemblance enables them to interact with enzymes and receptors, influencing biological processes.
  • Multifunctional Properties: The presence of the pyrimidinone moiety suggests potential antioxidant activity, which can protect cells from oxidative stress. This aspect is particularly valuable in pharmaceutical research, especially for developing treatments for diseases linked to oxidative damage.
  • Synthetic Versatility: The synthesis pathways for compounds in this class offer extensive opportunities for modifications. Such flexibility allows chemists to tailor the compound’s properties for specific applications, ranging from agricultural chemistry to materials science.
  • Catalytic Potential: Some studies indicate that similar structures can act as catalysts in organic reactions, enhancing efficiency and selectivity. This could pave the way for more sustainable chemical processes in the future.
  • Research Trends: The focus on tailored nitrogen-containing compounds (like pyrimidinones) has surged in recent years, as they are significant in the development of novel drugs, particularly antiviral and anticancer therapies.

In conclusion, sodium; 5-allyl-5-(1-methylbutyl)-4,6-dioxo-1H-pyrimidin-2-olate is not just a mere chemical entity; it embodies a wealth of potential and multifunctional applications that continue to captivate researchers and chemists alike.