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Sodium thiopental

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Identification
Molecular formula
C11H17N2NaO2S
CAS number
71-73-8
IUPAC name
sodium;5-allyl-5-(cyclohexen-1-yl)-6-oxo-2-sulfanyl-pyrimidin-4-olate
State
State

Sodium thiopental is solid at room temperature and is often sold in powder form for reconstitution into an injectable solution. It is soluble in water.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.15
General information
Molecular weight
264.32g/mol
Molar mass
264.3380g/mol
Density
1.3000g/cm3
Appearence

Sodium thiopental is typically encountered as a yellow crystalline powder. It is the sodium salt of thiopental, a barbiturate, and is typically used in injectable form.

Comment on solubility

Solubility of Sodium 5-allyl-5-(cyclohexen-1-yl)-6-oxo-2-sulfanyl-pyrimidin-4-olate

The solubility of sodium 5-allyl-5-(cyclohexen-1-yl)-6-oxo-2-sulfanyl-pyrimidin-4-olate can be influenced by several factors, making it an intriguing compound to investigate. Here are some key points regarding its solubility:

  • Polarity: The presence of polar functional groups, like the sulfanyl group and the pyrimidinolate moiety, suggests that this compound may have some degree of water solubility.
  • Salt Formation: Being a sodium salt, it may exhibit enhanced solubility in water compared to its neutral form, as sodium salts typically dissolve well in aqueous solutions.
  • Hydrophobic Interactions: The cyclohexenyl substructure introduces a hydrophobic character, which may impede solubility in purely polar solvents, influencing the overall solubility profile.
  • pH Dependence: The solubility of the compound could vary significantly with changes in pH, especially due to the presence of the pyrimidinolate which can exist in different ionic forms.

It is important to emphasize that while the initial assessment suggests a moderate to high solubility in polar solvents, empirical data through solubility testing would be essential to establish precise solubility characteristics under varying conditions. Understanding these solubility properties is crucial for applications in pharmaceuticals, where bioavailability can be directly impacted by solubility behavior.

Interesting facts

Interesting Facts about Sodium; 5-allyl-5-(cyclohexen-1-yl)-6-oxo-2-sulfanyl-pyrimidin-4-olate

This intriguing compound blends the features of both a pyrimidine derivative and a sodium salt, presenting a fascinating intersection of organic and inorganic chemistry. The presence of the pyrimidine ring—a key structure in many biological systems—suggests potential biochemical significance.

Key Features:

  • Functional Groups: This compound features an allyl group, imparting unique reactivity that could be exploited in various synthetic pathways or biological activity.
  • Thionyl and Oxy Groups: The presence of a sulfanyl group and an oxo group enhances the electrophilic and nucleophilic character of this compound, paving the way for potential applications in drug development.
  • Cyclohexene Moiety: The cyclohexenyl group adds to the compound's structural diversity and can influence its interaction with enzymes or receptors in biological systems.

Moreover, the sodium salt form of this compound could enhance its solubility and bioavailability, making it more applicable for pharmaceutical purposes. Its complex structure might also promote interesting interactions in medicinal chemistry, potentially leading to novel therapeutic agents.

As we explore this compound further, it is paramount to consider not only its chemical properties but also the applications that may arise from its unique structure. The fusion of organic and inorganic elements here typifies the creativity found in modern chemistry.

Overall, sodium; 5-allyl-5-(cyclohexen-1-yl)-6-oxo-2-sulfanyl-pyrimidin-4-olate stands as a compelling example of how intricate molecular design can lead to exciting developments in science.