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Sodium thiopental

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Identification
Molecular formula
C11H17N2NaO2S
CAS number
71-73-8
IUPAC name
sodium;5-allyl-5-isopropyl-4,6-dioxo-1H-pyrimidin-2-olate
State
State

At room temperature, sodium thiopental is generally in a solid crystalline state. When prepared for use, it is often dissolved to create a liquid solution for intravenous administration.

Melting point (Celsius)
161.00
Melting point (Kelvin)
434.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
264.21g/mol
Molar mass
264.2050g/mol
Density
1.0900g/cm3
Appearence

Sodium thiopental is typically encountered as a white or yellowish crystalline powder. It is odorless and has a bitter taste. In solution, it appears as a clear or slightly yellow liquid, depending on the concentration and storage conditions.

Comment on solubility

Solubility of Sodium 5-Allyl-5-Isopropyl-4,6-Dioxo-1H-Pyrimidin-2-Olate

The solubility of sodium 5-allyl-5-isopropyl-4,6-dioxo-1H-pyrimidin-2-olate is influenced by various factors that can determine its behavior in different solvents. Here are some key points to consider:

  • Polar Solvents: This compound tends to exhibit notable solubility in polar solvents, such as water, due to the presence of polar functional groups in its structure.
  • Non-Polar Solvents: Conversely, it shows limited solubility in non-polar solvents, such as hexane. This can be attributed to the lack of affinity between the compound's polar regions and the non-polar environment.
  • Temperature Dependency: The solubility may also vary with temperature; generally, increasing temperature can enhance solubility for many compounds.
  • pH Influence: The solubility might be affected by the pH of the solution, as the compound contains acidic and basic moieties which could ionize depending on the pH level.

In summary, understanding the solubility of sodium 5-allyl-5-isopropyl-4,6-dioxo-1H-pyrimidin-2-olate is crucial for its application in various chemical contexts. It highlights the importance of choosing the appropriate solvent for effective use, as well as considering environmental conditions that could affect its solubility.

Interesting facts

Interesting Facts about Sodium; 5-Allyl-5-Isopropyl-4,6-Dioxo-1H-Pyrimidin-2-Olate

The compound known as sodium; 5-allyl-5-isopropyl-4,6-dioxo-1H-pyrimidin-2-olate is a fascinating addition to the realm of organic and medicinal chemistry, primarily due to its structure and potential applications.

Structural Features

This compound contains a unique pyrimidine base, which is significant in various biological processes. Its structure includes:

  • Allyl and Isopropyl Substituents: These groups enhance the reactivity and lipophilicity of the compound, potentially affecting its interactions with biological membranes.
  • Dioxo Groups: The presence of two keto groups contributes to the compound's chemical activity and stability.

Potential Applications

Due to its structural characteristics, this compound may have implications in various fields, including:

  • Pharmaceutical Development: Compounds that contain pyrimidine derivatives are known to exhibit antifungal, antiviral, and anticancer activities.
  • Agricultural Chemistry: The unique properties of this compound could signal its potential use in developing new agrochemicals.

Biological Relevance

The compound’s structural similarities to crucial biomolecules highlight its possible role in:

  • Nucleotide Synthesis: Pyrimidines are vital components in the synthesis of nucleotides, which are essential for DNA and RNA formation.
  • Metabolic Pathways: Understanding its interactions might reveal new insights into metabolic processes affecting cellular functions.

This compound exemplifies how organic chemistry intertwines with fields such as biochemistry and pharmacology, representing the delicate dance between structure and function. As we continue to discover and characterize compounds like sodium; 5-allyl-5-isopropyl-4,6-dioxo-1H-pyrimidin-2-olate, we unlock further potential for innovative applications and scientific advancement.