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Meticillin sodium

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Identification
Molecular formula
C17H19N2NaO6S
CAS number
132-93-4
IUPAC name
sodium;6-[[2-(hydroxymethylamino)-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
State
State

At room temperature, the compound is a solid.

Melting point (Celsius)
216.20
Melting point (Kelvin)
489.35
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
445.44g/mol
Molar mass
445.4370g/mol
Density
1.3201g/cm3
Appearence

The compound appears as a white or off-white crystalline powder.

Comment on solubility

Solubility of Sodium 6-[[2-(hydroxymethylamino)-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

The solubility of sodium 6-[[2-(hydroxymethylamino)-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate is an important aspect to consider in various applications. This compound exhibits unique solubility characteristics due to its complex structure, which may influence its behavior in different solvents.

Factors Affecting Solubility:

  • Polarity: Given the presence of polar functional groups like -OH and -NH2, this compound is likely to demonstrate increased solubility in polar solvents such as water.
  • pH Levels: Solubility can be affected by the pH of the solution, especially since amino compounds can undergo protonation or deprotonation.
  • Temperature: Higher temperatures generally increase solubility for many compounds, making experimental conditions critical for determining the solubility profile.

The compound's **sodium** salt form indicates potential for increased aqueous solubility, which is often advantageous for pharmaceutical uses. Additionally, the presence of the aromatic phenyl group can create hydrophobic interactions that may influence solubility behaviors when mixed with non-polar solvents.

In summary, the solubility of this compound can be generalized as follows:

  1. Highly soluble in water due to ionic and polar interactions.
  2. Variable solubility in organic solvents depending on solvent polarity.
  3. Influenced by temperature and pH conditions.

Understanding these solubility properties is crucial for effective application in formulations and various chemical processes.

Interesting facts

Interesting Facts about Sodium;6-[[2-(hydroxymethylamino)-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

This intriguing compound, often referred to in the context of antibiotic research, exhibits several noteworthy features that are of particular interest to chemists and pharmacologists alike. Here are some engaging insights:

  • Multifaceted Structure: The compound contains a complex bicyclic structure, which is essential for its biological activity. Its unique framework involves a thiazolidine and a bicycloheptane ring, contributing to its distinct chemical characteristics.
  • Biological Relevance: Due to its arrangement, this compound is closely related to several classes of antibiotics. It is studied for its potential to combat bacterial resistance, making it a focus in pharmaceutical development.
  • Functional Groups: The presence of functional groups such as hydroxymethylamino and carboxylate enhances the compound's ability to interact with biological targets, which is crucial in medicinal chemistry.
  • Sodium Salts: The sodium salt form is often used for its enhanced solubility and bioavailability, which can significantly improve its pharmacokinetic properties.
  • Continued Research: Ongoing studies aim to explore its mechanism of action, resistance patterns, and potential applications in treating various infections, particularly those resistant to conventional antibiotics.

In summary, the compound represents a fascinating intersection of organic chemistry and pharmacology, embodying the complexities of drug design and the challenges of antibiotic resistance in modern medicine. Its structural motifs are not only of academic interest but also hold significant promise for future therapeutic advancements.