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Sodium estrone sulfate

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Identification
Molecular formula
C18H21NaO5S
CAS number
438-67-5
IUPAC name
sodium;[(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfate
State
State

At room temperature, sodium estrone sulfate is typically found in a solid state, often in the form of a powder or granulated crystals.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
440.53g/mol
Molar mass
440.5270g/mol
Density
1.4900g/cm3
Appearence

Sodium estrone sulfate typically appears as a white or off-white powder. It may also take the form of crystals. The compound is solid at room temperature and is usually soluble in water and some other polar solvents.

Comment on solubility

Solubility of Sodium ([(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfate)

The solubility of a compound such as sodium ([(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfate) can significantly influence its applications and behavior in various environments. When evaluating the solubility of this particular sulfate compound, several key aspects should be considered:

  • Ionic Nature: As a sodium salt, it is likely to exhibit good solubility in water due to the ionic interactions between the sodium ions and water molecules.
  • Hydrophilicity of the Sulfate Group: The presence of the sulfate group typically enhances solubility because sulfates have a strong affinity for water.
  • Overall Structure: The complex structure of the organic portion may introduce steric hindrance, potentially affecting solubility. However, the sulfate's negative charge often compensates for these steric effects.

In summary, the solubility of sodium ([(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfate) is likely to be relatively high, making it suitable for various applications, especially in biochemical systems, where its dissolved form can interact efficiently with biological molecules. Notably, the degree of solubility can vary widely based on temperature, pH, and the presence of other ions in solution.

Interesting facts

Interesting Facts about Sodium [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] Sulfate

This intriguing compound is a sulfate ester, highlighting the versatility and complexity of organic chemistry. Here are some fascinating aspects about it:

  • Biological Relevance: The compound is closely related to steroid hormones, which play crucial roles in human health. Steroids, including variations with sulfate groups, are essential for various physiological processes such as metabolism, immune function, and development.
  • Structural Complexity: This compound exhibits a multi-ring structure, part of a larger family of polycyclic compounds. Its intricate stereochemistry, indicated by the (8R,9S,13S,14S,17S) configuration, highlights how small changes in molecular arrangement can lead to significant biological differences.
  • Research Applications: Sulfated steroids are of great interest in pharmacological research. They may influence biological pathways and exhibit different activity profiles compared to their unconjugated forms, making them targets for drug discovery.
  • Role in Signaling: As a sulfate ester, this compound can participate in signaling mechanisms within cells, potentially affecting processes such as gene expression or cell differentiation.
  • Environmental Considerations: Studying the metabolism and breakdown of such complex molecules in environmental contexts can provide insights into how similar compounds behave in nature and their impact on ecological systems.

In conclusion, sodium [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfate is a prime example of how understanding chemical structures can lead to discoveries that bridge the fields of chemistry, biology, and environmental science. As a result, compounds like these are continually explored amidst their complex interactions and biological significance.