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N-Chlorosulfonamide sodium salt

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Identification
Molecular formula
C6H5ClNNaO2S
CAS number
127-81-3
IUPAC name
sodium;benzenesulfonyl(chloro)azanide
State
State

At room temperature, N-Chlorosulfonamide sodium salt is a solid. It remains stable under normal conditions when stored properly.

Melting point (Celsius)
50.00
Melting point (Kelvin)
323.15
Boiling point (Celsius)
265.10
Boiling point (Kelvin)
538.25
General information
Molecular weight
197.59g/mol
Molar mass
197.5900g/mol
Density
1.6940g/cm3
Appearence

The compound typically appears as a white to off-white crystalline solid. It can have a slightly pungent odor associated with sulfonamide compounds.

Comment on solubility

Solubility of Sodium Benzenesulfonyl(chloro)azanide

Sodium benzenesulfonyl(chloro)azanide is a compound with intriguing solubility properties. Understanding its solubility can provide insights into its behavior in various chemical environments. Here are some key points:

  • Solubility in Water: This compound is generally expected to be soluble in water due to the presence of the sodium ion, which enhances its interaction with polar solvents. The sulfonyl group also contributes to its affinity for water.
  • Effect of Temperature: Solubility can increase with temperature, which is a common characteristic of many ionic compounds. Warmer conditions may facilitate dissolution.
  • Solvent Polarity: The solubility profile might vary significantly in non-polar solvents. Non-polar solvents likely do not dissolve this compound effectively due to its ionic nature.
  • pH Sensitivity: Changes in pH could affect the solubility of sodium benzenesulfonyl(chloro)azanide, potentially leading to different degrees of ionization and subsequent solubility changes.

In summary, sodium benzenesulfonyl(chloro)azanide demonstrates appreciable solubility in polar solvents like water, influenced by ionic interactions, temperature variations, and the chemical environment. Therefore, careful consideration should be taken when predicting its behavior in different solutions.

Interesting facts

Interesting Facts about Sodium Benzenesulfonyl(chloro)azanide

Sodium benzenesulfonyl(chloro)azanide is an intriguing compound that holds a unique position in the realm of synthetic chemistry. Here are some compelling insights into this compound:

  • Versatile Intermediate: This compound serves as a versatile intermediate in various chemical reactions, particularly in the synthesis of heterocycles and pharmaceuticals, showcasing the powerful role of sulfonamide derivatives in medicinal chemistry.
  • Functional Group Importance: The presence of the benzenesulfonyl group in its structure enhances its reactivity, making it an excellent candidate for nucleophilic substitution reactions, which are vital in constructing complex organic molecules.
  • Role in Drug Development: Compounds like sodium benzenesulfonyl(chloro)azanide are often explored for their potential in drug development. Their antibacterial and antifungal properties are well-documented, making them invaluable in the pharmaceutical industry.
  • Research Applications: Chemical researchers often investigate this compound in the context of new methodologies for incorporating sulfonamide groups into organic frameworks, which may lead to innovative therapeutic agents.
  • Safety Considerations: As with many chemical compounds, it is essential to handle sodium benzenesulfonyl(chloro)azanide with care due to its reactive nature; proper safety protocols should always be followed in a laboratory setting.

In summary, sodium benzenesulfonyl(chloro)azanide not only serves as a key building block in the synthesis of complex organic molecules but also highlights the intricate relationships between chemical structure and biological activity. As scientists continue to explore its potential applications, it remains a fascinating subject of study.