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Sulfacetamide sodium

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Identification
Molecular formula
C8H10N2NaO3S
CAS number
127-56-0
IUPAC name
sodium;N-(4-aminophenyl)sulfonylacetamide
State
State

At room temperature, Sulfacetamide sodium is in a solid state. It is generally handled in a moisture-regulated environment to prevent hygroscopic effects.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
281.00
Boiling point (Kelvin)
554.15
General information
Molecular weight
254.24g/mol
Molar mass
254.2400g/mol
Density
0.8848g/cm3
Appearence

Sulfacetamide sodium is typically a white to off-white crystalline powder. Its appearance can be granular, and it is often found in the form of a fine powder. This compound is known for its stability and solubility, which makes it suitable for various pharmaceutical applications.

Comment on solubility

Solubility of Sodium N-(4-Aminophenyl)sulfonylacetamide

Sodium N-(4-aminophenyl)sulfonylacetamide is an intriguing compound with notable solubility characteristics. When considering the solubility of this compound, the following points are particularly relevant:

  • Water Solubility: This compound is generally soluble in water, which can be attributed to the presence of the sodium cation and the sulfonamide group that facilitates hydrogen bonding with water molecules.
  • Solvent Compatibility: In addition to water, it may exhibit solubility in some polar organic solvents, although the extent of solubility can vary significantly depending on solvent properties.
  • Temperature Influence: Solubility can also be influenced by temperature; as with many compounds, increased temperatures tend to enhance solubility.

In summary, the solubility of sodium N-(4-aminophenyl)sulfonylacetamide is positively impacted by its ionic nature and functional groups, allowing it to dissolve readily in aqueous solutions. This makes it versatile for various applications, including pharmaceuticals, where solubility is a critical factor in bioavailability.

Interesting facts

N-(4-Aminophenyl)sulfonylacetamide: An Overview

N-(4-aminophenyl)sulfonylacetamide, often referred to by its shorthand nickname, is an intriguing compound with notable applications in various fields. This compound plays a significant role in medicinal chemistry and is often studied for its potential therapeutic properties.

Key Properties and Uses

  • Pharmaceutical Applications: This compound is frequently investigated for its use in drug development, particularly in the search for new analgesics and anti-inflammatory agents.
  • Research Interest: Scientists are particularly drawn to its ability to modulate biological pathways, making it a target for research into chronic pain and inflammatory conditions.
  • Versatile Chemistry: The sulfonamide functional group present in the compound contributes to its versatile reactivity, allowing chemists to modify its structure for optimization in pharmaceutical applications.

Chemical Insights

The compound contains both an amine and a sulfonyl group, making it a valuable point of study in the development of sulfonamide antibiotics. Such antibiotics have had a significant impact on modern medicine, providing treatment options for various bacterial infections. As stated by a renowned chemist, "Understanding the relationship between structure and function in such compounds is crucial for designing the next generation of therapeutics."

Historical Context

Interestingly, the first sulfonamide drug, Prontosil, was discovered in the 1930s, marking a revolutionary shift in the treatment of bacterial infections. N-(4-aminophenyl)sulfonylacetamide, with its distinct structural features, is a modern continuation of this legacy, representing a crucial area of ongoing research.

In conclusion, N-(4-aminophenyl)sulfonylacetamide is more than just a chemical compound; it is a molecule with a rich history and exciting future potential in the realms of pharmaceutical sciences. Its study opens doors to new treatments and a better understanding of its underlying mechanisms.

Synonyms
PD063876
NS00079302