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Teriflunomide

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Identification
Molecular formula
C12H14N2O3
CAS number
108605-62-5
IUPAC name
tert-butyl N-[3-(dimethylcarbamoylamino)phenyl]carbamate
State
State

At room temperature, Teriflunomide is in a solid state.

Melting point (Celsius)
166.00
Melting point (Kelvin)
439.10
Boiling point (Celsius)
394.50
Boiling point (Kelvin)
667.60
General information
Molecular weight
270.31g/mol
Molar mass
270.3130g/mol
Density
1.2280g/cm3
Appearence

Teriflunomide typically appears as a white to pale yellow powder.

Comment on solubility

Solubility of tert-butyl N-[3-(dimethylcarbamoylamino)phenyl]carbamate

The solubility of tert-butyl N-[3-(dimethylcarbamoylamino)phenyl]carbamate is influenced by several key factors, typically including polarity, structure, and intermolecular interactions. Here’s what you need to consider:

  • Polarity: The presence of both a tert-butyl group and a dimethylcarbamoyl group suggests that the molecule may exhibit a balance of polar and non-polar characteristics, potentially affecting solubility in various solvents.
  • Hydrophilicity vs. Hydrophobicity: The dimethylcarbamoyl group is likely to contribute to hydrophilicity due to its ability to form hydrogen bonds with water, while the bulky tert-butyl group may enhance hydrophobic interactions.
  • Solvent Compatibility: This compound could be expected to show greater solubility in organic solvents such as acetone, ethanol, or chloroform, rather than in polar solvents like water, due to its structural design.
  • Temperature Dependence: The solubility might also vary with temperature – generally, organic compounds tend to become more soluble in warmer conditions, leading to a better dissolution in organic solvents.

In summary: The solubility behavior of tert-butyl N-[3-(dimethylcarbamoylamino)phenyl]carbamate can be complex due to its mixed polar and non-polar characteristics. Understanding this compound's solubility will be crucial for its applications in various chemical processes and formulations.

Interesting facts

Interesting Facts about Tert-Butyl N-[3-(Dimethylcarbamoylamino)phenyl]carbamate

Tert-butyl N-[3-(dimethylcarbamoylamino)phenyl]carbamate is a fascinating compound that plays a significant role in various fields of chemistry and pharmaceuticals. Below are some intriguing aspects of this chemical:

  • Pharmaceutical Application: This compound exhibits potential as a pharmaceutical agent, particularly in drug design and development. Its unique structure is advantageous in modifying biological properties, paving the way for innovative therapeutic solutions.
  • Structure-Activity Relationship: The presence of tert-butyl and dimethylcarbamoyl groups contributes to the compound's stability and reactivity. Understanding how these parts impact its function can lead to more effective compounds in medical science.
  • Enzyme Inhibition: Research into compounds like this has highlighted their ability to inhibit various enzymes, making them instrumental in targeting specific biological pathways associated with diseases.
  • Analytical Chemistry: This compound serves as a valuable subject in analytical chemistry studies. Techniques such as mass spectrometry and NMR spectroscopy can be employed to unveil its structural intricacies and interaction with other substances.
  • Synthesis Challenges: The synthesis of tert-butyl N-[3-(dimethylcarbamoylamino)phenyl]carbamate presents several challenges, requiring careful control of reaction conditions to yield a pure product. These challenges stimulate innovation in synthetic methods and techniques.
  • Emerging Research: New studies are continually being conducted to explore the effects of this compound in various biological systems, offering promising avenues for future research in medicinal chemistry.

In conclusion, tert-butyl N-[3-(dimethylcarbamoylamino)phenyl]carbamate is more than just a chemical compound; it embodies the intersection of clinical research, synthetic chemistry, and bioactivity. As scientists continue to delve deeper into its properties, the potential for groundbreaking discoveries remains vast. As one researcher aptly stated, "The journey of understanding compounds like this is what makes science not only a pursuit of knowledge but also a quest for solutions."

Synonyms
tert-butyl N-[3-(dimethylcarbamoylamino)phenyl]carbamate
N'-(3-{[tert-Butoxy(hydroxy)methylidene]amino}phenyl)-N,N-dimethylcarbamimidic acid
12705-28-1
SCHEMBL10548085
CHEBI:81743
DTXSID70925771
C18433
Q22808294