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tert-Butylurea

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Identification
Molecular formula
C5H12N2O
CAS number
6321-31-9
IUPAC name
tert-butylurea
State
State

At room temperature, tert-butylurea is in a solid state.

Melting point (Celsius)
109.00
Melting point (Kelvin)
382.15
Boiling point (Celsius)
198.00
Boiling point (Kelvin)
471.15
General information
Molecular weight
115.16g/mol
Molar mass
115.1580g/mol
Density
1.0990g/cm3
Appearence

tert-Butylurea is a white crystalline solid.

Comment on solubility

Solubility of tert-butylurea

tert-Butylurea, with the chemical formula (CH3)3CN2O, exhibits unique solubility characteristics that are worth noting:

  • Water Solubility: tert-Butylurea is appreciably soluble in water, primarily due to the presence of the urea functional group, which can form hydrogen bonds with water molecules.
  • Solvent Compatibility: It is also soluble in a variety of organic solvents, including alcohols and ethers, further demonstrating its polar nature. This solubility in polar solvents enhances its utility in various chemical applications.
  • Temperature Dependence: The solubility of tert-butylurea typically increases with temperature, a common trend observed in many solids when dissolved in liquids. This characteristic allows for better solubility at elevated temperatures.

In summary, tert-butylurea's solubility can be described as quite versatile, making it a valuable compound in both laboratory and industrial settings. Its ability to dissolve in both aqueous and organic environments showcases its importance and versatility in chemical synthesis.

Interesting facts

Interesting Facts about tert-butylurea

tert-butylurea, a versatile organic compound, is a derivative of urea that has garnered attention in various fields of chemistry. Here are some intriguing aspects of this compound:

  • Unique Structure: tert-butylurea features a tert-butyl group attached to the nitrogen atom of urea, resulting in a distinct steric configuration that influences its reactivity and interactions with other molecules.
  • Industrial Applications: This compound is used in the synthesis of pharmaceuticals and agrochemicals, acting as an important building block in the development of biologically active substances.
  • Polarity and Solubility: The presence of both a hydrophobic tert-butyl group and a hydrophilic urea group allows for fascinating polarity characteristics, making it an interesting subject for solubility studies in different solvents.
  • Biological Relevance: Some studies explore the potential of tert-butylurea as a stabilizer in biochemical applications, particularly concerning protein folding and stability.
  • Research Opportunities: Due to its reactivity and structural properties, tert-butylurea serves as a subject of ongoing research in studies relating to supramolecular chemistry and molecular recognition.

As a chemist or student delving into organic synthesis, understanding compounds like tert-butylurea opens doors to exploring innovative chemical processes and molecular interactions. Its unique characteristics encourage a deeper inquiry into how even subtle structural variations can lead to significant functional changes.

Synonyms
tert-Butylurea
N-tert-Butylurea
1118-12-3
(1,1-Dimethylethyl)urea
Urea, (1,1-dimethylethyl)-
UREA, tert-BUTYL-
1-tert-Butylurea
Urea, N-(1,1-dimethylethyl)-
NSC 4604
EINECS 214-257-3
N-(1,1-dimethylethyl)urea
BRN 1744501
T81TP489AF
DTXSID0044365
NSC-4604
DTXCID8024365
4-04-00-00665 (Beilstein Handbook Reference)
214-257-3
tert-butyl urea
1-(Tert-butyl)urea
MFCD00025448
t-butylurea
NSC4604
tert-butyl isourea
Tert-Butylurea; N-tert-Butylurea
N-(tert-butyl)urea
Urea,1-dimethylethyl)-
UNII-T81TP489AF
SCHEMBL23828
CHEMBL3184658
SCHEMBL17011644
N-tert-Butylurea, >=97.0%
Tox21_302081
AKOS000120185
NCGC00255818-01
CAS-1118-12-3
DB-041007
CS-0329615
NS00015750
G74757
F1744-0124
Z104473904