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Tetralin-5-amine

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Identification
Molecular formula
C10H13N
CAS number
5296-60-4
IUPAC name
tetralin-5-amine
State
State

At room temperature, tetralin-5-amine is typically in a liquid state due to its relatively low melting point. However, it can also be observed as a solid at slightly lower temperatures. Its liquid state is characterized by its moderately viscous nature.

Melting point (Celsius)
21.00
Melting point (Kelvin)
294.15
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.15
General information
Molecular weight
133.19g/mol
Molar mass
133.1930g/mol
Density
1.0450g/cm3
Appearence

Tetralin-5-amine typically presents as a colorless to pale yellow liquid, although it might crystallize into a solid under certain conditions. It is recognized for its amine group, which can slightly affect its appearance and make it more susceptible to oxidation when exposed to air.

Comment on solubility

Solubility of Tetralin-5-amine

Tetralin-5-amine, with its unique structure, exhibits interesting solubility properties. Solubility is a crucial factor in determining the compound's applicability in various fields, including pharmaceuticals and material science. Here are some key points regarding its solubility:

  • Polar vs. Nonpolar Solvents: Tetralin-5-amine is expected to have higher solubility in nonpolar solvents due to the presence of tetrahydronaphthalene, which is nonpolar in nature.
  • Hydrogen Bonding: The amine group (-NH2) is capable of forming hydrogen bonds, which may enhance solubility in polar solvents like water under certain conditions.
  • Temperature Effects: Solubility tends to increase with temperature, so higher temperatures could improve the solubility of tetralin-5-amine in various solvents.
  • pH Influence: The solubility might also be influenced by pH levels, particularly in aqueous environments where the amine can accept protons, affecting its ionization state.

In summary, while tetralin-5-amine shows favorable solubility in nonpolar solvents due to its hydrophobic structure, it may also dissolve in polar solvents under specific conditions. This dual solubility profile renders it versatile for diverse applications, making it an intriguing compound for further study.

Interesting facts

Interesting Facts about Tetralin-5-amine

Tetralin-5-amine, a fascinating organic compound, is a derivative of tetralin, which is known for its unique bicyclic structure. Here are some intriguing highlights about this compound:

  • Structural Significance: The presence of an amino group (-NH2) at the 5-position of the tetralin framework introduces diverse chemical reactivity, opening avenues for various applications.
  • Biological Activity: Compounds similar to tetralin-5-amine are often explored in medicinal chemistry for their potential therapeutic effects. They may exhibit interesting biological activities, such as antimicrobial or anticancer properties, making them valuable in drug design.
  • Synthetic Pathways: The synthesis of tetralin-5-amine can involve various methodologies, including reduction and amination reactions, often reflecting the creative nature of organic synthesis in the laboratory.
  • Research Applications: Tetralin derivatives like tetralin-5-amine are frequently utilized as intermediates in the production of complex molecules, which can lead to advances in materials science and pharmaceuticals.
  • Potential as a Solvent: The non-polar character of tetralin allows it to be a useful solvent in chemical reactions, particularly when working with organic compounds.

In summary, tetralin-5-amine is more than just another amine; its unique structure and reactivity profiles offer invaluable opportunities in both research and practical applications. As the field of organic chemistry continues to evolve, compounds like tetralin-5-amine stand at the forefront of innovation and discovery.

Synonyms
5,6,7,8-Tetrahydro-1-naphthylamine
2217-41-6
5-Aminotetralin
1-Amino-5,6,7,8-tetrahydronaphthalene
5-Tetralylamine
1-Naphthalenamine, 5,6,7,8-tetrahydro-
5-Amino-1,2,3,4-tetrahydronaphthalene
1-NAPHTHYLAMINE, 5,6,7,8-TETRAHYDRO-
5-Tetralinylamine
5,6,7,8-Tetrahydro-1-naphthalenamine
alpha-Tetrahydronaphthylamine
NSC 53503
EINECS 218-713-2
BRN 0387264
U0L74S8K6G
NSC-53503
1,2,3,4-Tetrahydro-5-naphthylamine
1,2,3,4-Tetrahydro-5-naphthalenamine
DTXSID70176701
4-12-00-02934 (Beilstein Handbook Reference)
5,6,7,8-tetrahydro-1-naphthalenylamine
1,2,3,4-TETRAHYDRO-5-AMINONAPHTHALENE
DTXCID6099192
1-Naphthalenamine, 5,6,7,8-tetrahydro-(9CI)
218-713-2
5,6,7,8-tetrahydronaphthalen-1-amine
.alpha.-Tetrahydronaphthylamine
MFCD00001736
tetralin-5-amine
5,6,7,8-tetrahydronaphthylamine
UNII-U0L74S8K6G
WLN: L66&TJ BZ
SCHEMBL751800
5,6,7,8-tetrahydro-naphthylamine
NSC53503
STR02247
1-Naphthylamine,6,7,8-tetrahydro-
STK688564
1-Amino-5,7,8-tetrahydronaphthalene
5-Amino-1,3,4-tetrahydronaphthalene
1-Naphthalenamine,6,7,8-tetrahydro-
AKOS000120467
AC-5737
1-amino-5,6,7,8-tetrahydronaphtalene
5-amino-1,2,3,4-tetrahydronapthalene
1-Amino-5,6,7,8-tetrahydronaphthaline
5,6,7,8-tetrahydronaphthalen-1-ylamine
TS-01932
5,6,7,8-Tetrahydro-1-naphthalenamine #
5,6,7,8-Tetrahydro-naphthalen-1-ylamine
5,6,7,8-tetrahydro-naphthalen-1-yl-amine
DB-045833
5,6,7,8-Tetrahydro-1-naphthylamine, 99%
A0995
A4767
naphthalene, 5-amino-1,2,3,4-tetrahydro-
NS00027089
EN300-21575
Z104502914
InChI=1/C10H13N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h3,5,7H,1-2,4,6,11H