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Thiazolidine

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Identification
Molecular formula
C3H7NS
CAS number
504-78-9
IUPAC name
thiazolidine
State
State

At room temperature, thiazolidine is typically in a liquid state due to its relatively low melting point.

Melting point (Celsius)
-26.00
Melting point (Kelvin)
247.15
Boiling point (Celsius)
122.50
Boiling point (Kelvin)
395.65
General information
Molecular weight
89.16g/mol
Molar mass
89.1600g/mol
Density
1.1139g/cm3
Appearence
Thiazolidine is a colorless to pale yellow liquid. It exhibits a characteristic amine-like odor and is hygroscopic, meaning it can readily absorb moisture from the air.
Comment on solubility

Solubility of Thiazolidine

Thiazolidine, with the chemical formula C3H7N1S1, showcases distinctive solubility characteristics that are important to understand for its applications and behavior in different environments.

Solubility Profile

Generally, thiazolidine is known to be:

  • Soluble in water: The polar nature of the thiazolidine structure allows it to interact favorably with water molecules, making it soluble at room temperature.
  • Soluble in organic solvents: It can also dissolve well in various organic solvents including ethanol and dimethyl sulfoxide, owing to its non-polar portions.

In the context of its solubility:

  • Factors influencing solubility include pH level, temperature, and the presence of other solutes.
  • The nature of solvation is determined by the hydrophilicity and lipophilicity of the compound.

As a result, the solubility of thiazolidine can showcase varied outcomes depending on environmental conditions, making it a compound of interest in fields like pharmaceuticals and materials science. To quote, "Understanding solubility is key to unlocking the full potential of chemical compounds."

This multifaceted solubility behavior, thus, opens up various avenues for research and application across different scientific domains.

Interesting facts

Interesting Facts About Thiazolidine

Thiazolidine is a fascinating compound that belongs to a class of organic compounds known for their sulfur-containing five-membered rings. This unique structure imparts distinct properties and behaviors, making it a subject of interest in various scientific fields.

Key Characteristics and Applications

  • Biological Significance: Thiazolidine compounds play a crucial role in many biological processes. Notably, they are involved in the synthesis of amino acids and are key intermediates in the metabolism of certain biomolecules.
  • Pharmaceutical Use: Thiazolidine derivatives have been studied for their potential in treating diabetes. These compounds can enhance insulin sensitivity, making them valuable in drug development.
  • Structural Versatility: The thiazolidine ring can easily undergo transformations, allowing chemists to synthesize a variety of functionalized derivatives, which can be tailored for specific applications.

Chemical Properties

Thiazolidine exhibits interesting reactivity due to the presence of both nitrogen and sulfur atoms in its structure. This includes:

  • Nucleophilic reactivity: The nitrogen atom can engage in nucleophilic attacks, leading to the formation of new chemical bonds.
  • Oxidation reactions: The sulfur atom can be oxidized, allowing for the generation of sulfoxides and sulfones that are useful in various organic syntheses.

Exciting Research

Research into thiazolidine derivatives continues to be a dynamic field, with ongoing studies aimed at:

  • Exploring their roles in metabolism and cellular signaling.
  • Developing novel therapeutic agents utilizing their unique molecular framework.
  • Investigation into their potential as natural products in medicinal chemistry.

As a compound that bridges organic chemistry and biochemistry, thiazolidine exemplifies how small changes in molecular structure can lead to profoundly different properties and applications. The exploration of its derivatives promises to unveil even more exciting discoveries in science!

Synonyms
THIAZOLIDINE
504-78-9
Tetrahydrothiazole
1-Thia-3-azacyclopentane
Thiazole, tetrahydro-
Thiazolidines
CCRIS 4275
EINECS 208-002-5
BRN 0102469
I320806BKW
NSC-357911
DTXSID10198447
4-27-00-00009 (Beilstein Handbook Reference)
NSC 357911
CHEBI:35622
CHEBI:38333
DTXCID40120938
208-002-5
inchi=1/c3h7ns/c1-2-5-3-4-1/h4h,1-3h
ogygfuaiiopwqd-uhfffaoysa-n
1,3-Thiazolidine
CHEMBL1916078
CHEBI:50120
MFCD00005211
UNII-I320806BKW
1,3-Thiazolidine; 1-Thia-3-azacyclopentane; Tetrahydrothiazole; Tetrahydro-thiazole
NSC357911
Thiazolidine, 95%
1,3-Thiazolidine #
1,3-thiazolidin-3-ium
ALBB-022614
BCP22810
HY-I0144
STR04848
BDBM50357214
AKOS005146302
CS-0006687
NS00022248
T0793
EN300-43043
H11361
Q413761