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Thiazolidine-4-carboxylic acid

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Identification
Molecular formula
C4H7NO2S
CAS number
1483-59-6
IUPAC name
thiazolidine-4-carboxylic acid
State
State

At room temperature, Thiazolidine-4-carboxylic acid is in a solid state, appearing as a white crystalline powder.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
359.40
Boiling point (Kelvin)
632.60
General information
Molecular weight
133.18g/mol
Molar mass
133.1840g/mol
Density
1.4550g/cm3
Appearence

Thiazolidine-4-carboxylic acid typically appears as a white crystalline solid. It may also be available as a powder.

Comment on solubility

Solubility of Thiazolidine-4-carboxylic Acid

Thiazolidine-4-carboxylic acid, with its unique structure, exhibits interesting solubility characteristics that are influenced by several factors. Here are some key points regarding its solubility:

  • Water Solubility: Thiazolidine-4-carboxylic acid is generally considered to be soluble in water mainly due to the presence of the carboxylic acid functional group, which can form hydrogen bonds with water molecules.
  • Solvent Dependence: Its solubility can greatly vary depending on the solvent used. For instance, it is known to be more soluble in alcohols and organic solvents compared to nonpolar solvents.
  • pH Influence: The pH of the solution can also affect solubility. At higher pH levels, the carboxylic acid group can deprotonate, leading to increased solubility in aqueous solutions.

As a result, we can say that the solubility behavior of thiazolidine-4-carboxylic acid is multifaceted and can be influenced by environmental conditions such as temperature and the nature of surrounding molecules.

Interesting facts

Interesting Facts about Thiazolidine-4-Carboxylic Acid

Thiazolidine-4-carboxylic acid is a unique compound that belongs to the class of thiazolidine derivatives, which are notable for their diverse biological activities. Here are some fascinating points to explore:

  • Biologically Active: This compound is recognized for its potential pharmacological properties, which include antioxidant and anti-inflammatory effects. Researchers are particularly interested in its implications for health and disease.
  • Protein Synthesis: Thiazolidine-4-carboxylic acid plays a crucial role in protein synthesis and metabolism due to its involvement in the production of cysteine, an amino acid vital for numerous biological processes.
  • Pharmaceutical Applications: It has garnered attention in medicinal chemistry as a scaffold for drug design, particularly in the development of treatments for various diseases.
  • Research Significance: Ongoing studies suggest that thiazolidine-4-carboxylic acid could have potential benefits in treating conditions such as diabetes and hypertension, making it a compound of interest in contemporary medical research.
  • Natural Occurrence: This compound can be found in certain natural products, which hints at its evolutionary significance and potential applications in herbal medicine.

As the field of chemistry progresses, the importance of compounds like thiazolidine-4-carboxylic acid continues to expand. Its multifaceted nature makes it an exciting subject for both chemists and pharmacologists alike, reminding us of the untapped potential that lies within the world of chemical compounds.

Synonyms
Timonacic
Thiazolidine-4-carboxylic acid
444-27-9
1,3-Thiazolidine-4-carboxylic acid
4-THIAZOLIDINECARBOXYLIC ACID
Detoxepa
Thioproline
Hepalidine
Tiazolidin
4-Carboxythiazolidine
Heparegene
Norgamem
Thiaproline
DL-Thiaproline
Timonacico
Norgamen
L-Thiazolidine-4-carboxylic acid
USAF C-1
Timonacic [INN]
T-4CA
Heparegen
Timonacicum
USAF A-3701
Heptaladine
Hepacom
Hepaldine
DL-Thiazolidinecarboxylic acid
NSC-25855
Timonacicum [INN-Latin]
Timonacico [INN-Spanish]
NSC 25855
Acide thiazolidine-4-carboxylique
EINECS 207-146-6
EINECS 242-945-3
Acide DL thiazolidine carboxylique-4
MFCD00128958
Timonacic (INN)
Thiazolidine-4-carboxylicacid
Hepacom (TN)
CCRIS 8099
E5913T3IBL
CHEBI:64564
Acide thiazolidine-4-carboxylique [French]
Thiazolidinecarboxylic acid
NSC25855
TIMONACIC [MI]
Acide DL thiazolidine carboxylique-4 [French]
TIMONACIC [MART.]
TIMONACIC [WHO-DD]
thiazolidine, 4-carboxy-
Timonacicum (INN-Latin)
Timonacico (INN-Spanish)
TIMONACIC (MART.)
L(-)-Thiazolidine-4-carboxylic acid
DTXSID9023675
Thiazolidinecarboxylic acid (VAN)
thiazolidin
UNII-E5913T3IBL
gamma-thiaproline
MFCD00005212
L-4-Thiazolidinecarboxylic acid, 98%
TIMONACIC [INCI]
4-thiazolidincarboxylic acid
SCHEMBL8356
WLN: T5M CSTJ EVQ
thiazolidine-4-caboxylic acid
Thiazolidin-4-carboxylic acid
4-thiazolidine carboxylic acid
CHEMBL358722
DTXCID603675
WLN: T5M CSTJ EVQ -L
DL-Thiazolidine-4-carboxylic acid
HMS3264C18
Pharmakon1600-01503320
AAA44427
ALBB-005988
BCP13616
HY-B1169
NSC758453
s4993
STK361805
AKOS000119343
AKOS016040292
racemic thiazolidine-4-carboxylic acid
1,3-Thiazolidine-4-carboxylic acid #
AB03779
CCG-213875
CS-8024
DB12856
NSC-758453
AS-13539
DA-78481
SBI-0207087.P001
4-Thiazolidinecarboxylic acid, (.+/-.)-
DB-048659
DB-335783
NS00080385
EN300-21404
D08601
D97373
ThiaZolidine-4-carboxylic acid (H-DL-ThZ-OH)
AB01563202_01
AH-232/20359048
L(-)-Thiazolidine-4-carboxylic acid;L-Thiaproline
SR-01000944258
SR-01000944258-1
BRD-A38592941-001-02-7
Q23637400
Z104495996
207-146-6
849052-64-8