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Thieno[2,3-c]pyridine

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Identification
Molecular formula
C7H5NS
CAS number
253-38-5
IUPAC name
thieno[2,3-c]pyridine
State
State

At room temperature, Thieno[2,3-c]pyridine exists as a solid. It is generally handled in its crystalline form.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
293.00
Boiling point (Kelvin)
566.15
General information
Molecular weight
135.18g/mol
Molar mass
133.1850g/mol
Density
1.1670g/cm3
Appearence

Thieno[2,3-c]pyridine is a heterocyclic compound which appears as a cyclic structure combining a thiophene ring fused to a pyridine ring. It is a crystalline solid and is typically yellow to light tan in color.

Comment on solubility

Solubility of Thieno[2,3-c]pyridine

Thieno2,3-c-pyridine is an intriguing aromatic heterocyclic compound that exhibits a distinct solubility profile influenced by its molecular structure. Understanding its solubility characteristics is crucial for applications in various fields, particularly organic chemistry and pharmaceuticals. Here are some key points regarding its solubility:

  • Solvent Compatibility: Thieno2,3-c-pyridine tends to be soluble in organic solvents such as ethanol, chloroform, and dimethyl sulfoxide (DMSO), making it useful in various organic reactions.
  • Water Solubility: This compound generally has low solubility in water due to its hydrophobic characteristics, stemming from its aromatic structure.
  • Temperature Effects: Similar to many organic compounds, the solubility of thieno2,3-c-pyridine can increase with temperature, facilitating its dissolution in solvents at elevated temperatures.
  • Ph Dependency: The solubility may also be influenced by the pH of the solution, creating opportunities for manipulation depending on the desired chemical environment.

In summary, the solubility behavior of thieno2,3-c-pyridine primarily highlights its solubility in non-aqueous solvents and emphasizes the relevance of environmental factors like temperature and pH. This information is invaluable for dosage formulation and synthesis in laboratory conditions.

Interesting facts

Interesting Facts about Thieno[2,3-c]pyridine

Thieno[2,3-c]pyridine is a fascinating compound that embodies the intersection of heterocyclic chemistry and pharmaceutical sciences. This compound is characterized by its unique bicyclic structure, which includes both a thiophene and a pyridine ring. Here are some noteworthy aspects:

  • Versatile Applications: Thieno[2,3-c]pyridine is not just a theoretical construct; it has significant applications in medicinal chemistry. Researchers are particularly interested in its potential as a scaffold for novel drug development, especially in the fields of neuropharmacology and anticancer research.
  • Biological Activity: Compounds derived from thieno[2,3-c]pyridine have been found to exhibit a range of biological activities, including anticancer, antibacterial, and anti-inflammatory properties. This makes them a subject of intense study for developing new therapeutic agents.
  • Synthesis Challenges: The synthesis of thieno[2,3-c]pyridine can be challenging due to its complex structure. Common methods involve sulfur and nitrogen heterocycles, and ongoing research is focused on making these synthetic processes more efficient.
  • Research Significance: Given the increasing importance of heterocycles in drug design, thieno[2,3-c]pyridine stands out as a promising candidate warranting further investigation. Its unique electronic properties and chemical reactivity open doors to creating compounds with enhanced functionality.

In summary, thieno[2,3-c]pyridine is a remarkable compound worthy of attention in the fields of chemistry and pharmacology. Its diverse applications, coupled with its intriguing structural features, make it a compound of choice for further explorations and innovations. As noted by researchers, "The discovery of novel compounds continues to fuel advancements in medicinal chemistry, and thieno[2,3-c]pyridine is poised to play a significant role."

Synonyms
Thieno[2,3-c]pyridine
272-12-8
Thieno(2,3-c)pyridine
6-Azabenzo[b]thiophene
6-AZATHIANAPHTHENE
MFCD01760492
DTXSID60181662
NSC 152396
NSC-152396
6-Azabenzo(b)thiophene
NSC152396
thieno[2,3-c]-pyridine
C2A49UZQ9T
SCHEMBL10970
DTXCID00104153
AKOS006341649
DS-1715
MB02036
PS-4157
SB36316
SY028707
DB-003788
CS-0006104
EN300-233967
AI-942/25121094
820-521-4