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sulfolane

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Identification
Molecular formula
C4H8O1S1
CAS number
126-33-0
IUPAC name
thiolane 1-oxide
State
State

At room temperature, sulfolane exists as a liquid but can crystallize upon cooling through its melting point (27.5 °C).

Melting point (Celsius)
27.50
Melting point (Kelvin)
300.70
Boiling point (Celsius)
285.50
Boiling point (Kelvin)
558.70
General information
Molecular weight
120.17g/mol
Molar mass
120.1720g/mol
Density
1.2600g/cm3
Appearence

Sulfolane is a colorless liquid at room temperature. It is also commonly referred to as a transparent, crystalline solid. Its appearance might also be described as an oily or viscous liquid, depending on the temperature.

Comment on solubility

Solubility of Thiolane 1-Oxide

Thiolane 1-oxide, with the chemical formula C4H8O1S1, displays notable solubility characteristics which can significantly influence its behavior in various chemical environments. Here’s a closer examination:

  • Polarity: The presence of both a sulfur atom and a hydroxyl group contributes to the compound's polarity, affecting its solubility in different solvents.
  • Solvent Compatibility: Thiolane 1-oxide is generally more soluble in polar solvents, such as water and alcohols, compared to nonpolar solvents like hexane.
  • Hydrogen Bonding: Its ability to engage in hydrogen bonding enhances its solubility in aqueous solutions, facilitating interactions with water molecules.
  • Concentration Factors: The degree of solubility can also be influenced by factors such as temperature and the concentration of the solvent.

In summary, the solubility of thiolane 1-oxide is an interplay of its molecular structure and environmental variables.

Interesting facts

Interesting Facts about Thiolane 1-oxide

Thiolane 1-oxide, often referred to in research contexts for its unique structural features and properties, is saturated with intriguing chemistry. As a member of the thiolether family, it showcases both sulfur and oxygen elements which contribute to its reactivity and behavior in various chemical environments. Here are some interesting aspects of this compound:

  • Cyclic Structure: Thiolane 1-oxide features a five-membered ring structure that includes sulfur and oxygen, offering a different set of reactivities compared to linear compounds.
  • Reactivity: The presence of the sulfur and oxygen atoms within the ring allows for interesting reaction pathways, particularly in nucleophilic substitution reactions, making it a valuable intermediate in organic synthesis.
  • Biological Relevance: Compounds containing thiolether functionalities, including thiolane 1-oxide, are studied for their potential roles in biological systems and as potential pharmaceuticals.
  • Industrial Applications: This compound and its derivatives may find applications in the production of agrochemicals and materials that require customized sulfur-containing functionalities.
  • Research Focus: Ongoing research is dedicated to enhancing our understanding of thiolane 1-oxide's properties, aiming to discover new applications and methodologies for its utilization.

As noted in various studies, "the investigation of sulfur-containing compounds like thiolane 1-oxide paves the way for innovative synthetic strategies and enhances our grasp of their practical applications in chemistry." This encapsulates the exciting potential of the compound in the realm of both academic and industrial chemistry.

Synonyms
Tetramethylene sulfoxide
1600-44-8
tetrahydrothiophene 1-oxide
Thiolane 1-oxide
Thiophane oxide
Tetrahydrothiophene oxide
THIOPHENE, TETRAHYDRO-, 1-OXIDE
Thiophane monoxide
Thiophane 1-oxide
Tetramethylene sulphoxide
NSC 65433
Thiophene, tetrahydro, 1-oxide
EINECS 216-493-2
MFCD00005477
BRN 0105274
AI3-62189
TETRAHYDRO-THIOPHENE-1-OXIDE
FL7PF5FLM2
DTXSID6061814
TETRAHYDROTHIOPHENE-1-OXIDE
5-17-01-00038 (Beilstein Handbook Reference)
NSC-65433
Tetrametylene sulfoxide
Thiolane 1oxide
Thiophane 1oxide
1-thiolan-1-one
Thiophene, 1-oxide
TMSO
Tetramethylenesulfoxide
1lambda-thiolan-1-one
1lambda4-thiolan-1-one
UNII-FL7PF5FLM2
Tetrahydrothiophene 1oxide
tetrahydrothiophen-1-oxide
WLN: T5STJ AO
Tetrahydrothiophene S-oxide
CHEMBL1207
NCIOpen2_000223
SCHEMBL27830
Tetrahydro-thiophene 1-oxide
Thiophene, tetrahydro, 1oxide
Thiophene,tetrahydro-,1-oxide
Thiophene-1-oxide, tetrahydro-
DTXCID6035152
CHEBI:138746
Tetrahydrothiophene 1-oxide, 96%
NSC65433
BDBM50224861
AKOS000121854
FS-4006
SY010164
DB-043445
CS-0207394
NS00015333
T0146
EN300-28865
D92307
Z278052312
216-493-2
QZT