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Thiophene-2-carboxamide

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Identification
Molecular formula
C5H5NOS
CAS number
4670-53-1
IUPAC name
thiophene-2-carboxamide
State
State
At room temperature, thiophene-2-carboxamide is typically found in a solid state. It is stable under standard temperature and pressure conditions, and should be stored accordingly to maintain its chemical properties.
Melting point (Celsius)
160.50
Melting point (Kelvin)
433.70
Boiling point (Celsius)
387.70
Boiling point (Kelvin)
660.90
General information
Molecular weight
125.16g/mol
Molar mass
125.1630g/mol
Density
1.3087g/cm3
Appearence
Thiophene-2-carboxamide is a crystalline solid that typically appears as off-white to light yellow in color. The compound is known for its distinct crystalline structure, which can appear more white when the crystals are more refined or pure.
Comment on solubility

Solubility of Thiophene-2-carboxamide

Thiophene-2-carboxamide, with the chemical formula C5H6N2S, exhibits interesting solubility characteristics that are worth noting. The solubility of a compound can greatly influence its applications and behavior in various chemical environments.

Key Points About Solubility

  • Solvent Compatibility: Thiophene-2-carboxamide tends to be soluble in polar solvents such as water and alcohols due to the presence of its amide functional group, which is known for its ability to form hydrogen bonds.
  • Temperature Effects: The solubility of this compound may increase with temperature, a common characteristic for many organic compounds.
  • pH Dependence: The solubility might also be influenced by pH; changes in acidity or basicity can lead to protonation or deprotonation of the amide group, altering its solubility profile.

In summary, the solubility of thiophene-2-carboxamide is attributed to its polar characteristics and the ability to interact favorably with various solvents. Understanding its solubility can aid in predicting its behavior in different chemical reactions and environments.

Interesting facts

Interesting Facts about Thiophene-2-Carboxamide

Thiophene-2-carboxamide is a fascinating compound that belongs to a class of heterocyclic organic molecules. Its structure comprises a thiophene ring, which is a five-membered aromatic ring containing one sulfur atom, combined with a carboxamide functional group. Here are some intriguing aspects of this compound:

  • Biological Activity: Thiophene derivatives are known for their diverse biological activities, including antimicrobial, antifungal, and anticancer properties. This makes them significant in the field of medicinal chemistry.
  • Material Science: The unique electronic properties of thiophene-containing compounds, including thiophene-2-carboxamide, lend themselves to applications in organic electronics and conducting polymers.
  • Functionalization: The carboxamide group can serve as a versatile handle for further functionalization, allowing chemists to synthesize a wide range of modified thiophene derivatives.
  • Research Significance: Studies of thiophene-2-carboxamide help us understand the reactivity and stability of sulfur-containing heterocycles, which is crucial for the development of new materials.

In summary, thiophene-2-carboxamide is not just another compound; it represents the intersection of chemistry, biology, and materials science. As researchers continue to explore its properties and applications, thiophene-2-carboxamide could unveil new avenues for innovation.

Synonyms
2-THIOPHENECARBOXAMIDE
Thiophene-2-carboxamide
5813-89-8
NSC 109369
BRN 0110153
DTXSID60206849
5-18-06-00162 (Beilstein Handbook Reference)
DTXCID40129340
denpqnawgqxkcu-uhfffaoysa-n
2-Thienylamide
2-Thenamide
2-(Aminocarbonyl)thiophene
MFCD00010425
thiophen-2-carboxamide
C5H5NOS
2-Thienylamide [French]
thiolamide
thiophenic imine
2-Thiophenecarboxamide, 99%
BIDD:GT0638
SCHEMBL120212
ALBB-019885
NSC109369
AKOS000265960
FT70707
NSC-109369
SB66924
SS-3260
SY048620
DB-053156
CS-0181836
T1252
EN300-49198
D85795
Z33546758
F1084-0215