Skip to main content

Methylene Blue

ADVERTISEMENT
Identification
Molecular formula
C16H18ClN3S
CAS number
61-73-4
IUPAC name
trimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium;chloride
State
State

At room temperature, methylene blue is typically found in a solid state as a crystalline powder. In its dissolved form, it becomes a vivid blue liquid.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
319.85g/mol
Molar mass
319.8510g/mol
Density
1.0000g/cm3
Appearence

Methylene Blue appears as a dark green crystalline powder in its solid form. When dissolved in water, it forms a deep blue solution. It can also appear as crystals ranging from blue to black in color when in hydrated forms.

Comment on solubility

Solubility of Trimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium Chloride

Trimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium chloride, often abbreviated as TMA-phenothiazine chloride, exhibits solubility characteristics that are influenced by both its ionic nature and the organic components of its structure. Here are some key points to consider regarding its solubility:

  • Water Solubility: Being a quaternary ammonium salt, TMA-phenothiazine chloride is expected to be soluble in water due to the presence of the ionic +N (trimethylammonium) group.
  • Solvent Compatibility: This compound may show enhanced solubility in polar organic solvents, such as ethanol and methanol, compared to non-polar solvents.
  • Temperature Effects: The solubility may increase with temperature, which is a common phenomenon for many ionic compounds.
  • pH Influence: The solubility can be affected by pH, as changes in acidity or basicity may influence the protonation state of certain functional groups within the phenothiazine moiety.

In conclusion, it can be stated that the solubility of trimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium chloride is a result of its ionic characteristics and interactions with solvents, making it an interesting compound for various applications in solution. As with many compounds, factors such as temperature, pH, and the nature of the solvent all play critical roles in the overall solubility behavior.

Interesting facts

Interesting Facts about Trimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium Chloride

Trimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium chloride is a fascinating compound with intriguing applications and properties. Here are some notable aspects of this unique quaternary ammonium salt:

  • Chemical Structure: The compound features a trimethylammonium group, which is known for its cationic nature. This cation is a fundamental component that interacts with other molecules, influencing their behavior in various environments.
  • Phenothiazine Derivative: It is derived from phenothiazine, a well-known structure in medicinal chemistry that exhibits a range of biological activities, including antipsychotic and antihistaminic effects. This characteristic makes the compound particularly interesting for pharmacological studies.
  • Biological Significance: Compounds related to phenothiazine, including this one, have been researched for their potential in treating disorders such as schizophrenia and anxiety. The quaternary ammonium form enhances solubility and bioavailability, furthering its therapeutic potential.
  • Quaternary Ammonium Compounds: Being a quaternary ammonium compound, it possesses surfactant properties. These compounds are often employed in medical applications, such as disinfectants and antiseptics, due to their ability to disrupt microbial membranes.
  • Research Applications: The unique structure of this compound allows it to be utilized in various scientific studies, particularly in organic synthesis and medicinal chemistry. Scientists often explore how modifications to the phenothiazine core can lead to new compounds with enhanced or altered biological activities.

In summary, trimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium chloride is more than just a compound; it is a blend of chemistry and potential health benefits. Its significance in research and medicine continues to inspire scientists as they explore its myriad possibilities.

Synonyms
THIAZINAMIUM CHLORIDE
4320-13-2
WY-460E
Thiazinamium chloride [USAN]
trimethyl(1-phenothiazin-10-ylpropan-2-yl)azanium;chloride
89SV0QH69Q
Thiazinamium chloride (USAN)
Trimethyl(1-methyl-2-phenothiazin-10-ylethyl)-ammonium chloride
N,N,N-Trimethyl-1-(10H-phenothiazin-10-yl)propan-2-aminium chloride
UNII-89SV0QH69Q
SCHEMBL635014
CHEMBL2107499
DTXSID40962956
HY-U00267
AKOS040740257
CS-7198
DA-68142
D06107
Q27270064
10H-Phenothiazine-10-ethanaminium, N,N,N,alpha-tetramethyl-, chloride
10H-PHENOTHIAZINE-10-ETHANAMINIUM, N,N,N,.ALPHA.-TETRAMETHYL-, CHLORIDE(1:1)