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Trihexyphenidyl iodide

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Identification
Molecular formula
C20H25F3NO.CHI
CAS number
66-54-2
IUPAC name
trimethyl-[2-[phenyl-[3-(trifluoromethyl)phenyl]methoxy]ethyl]ammonium;iodide
State
State

At room temperature, Trihexyphenidyl iodide is in a solid state, appearing as a crystalline powder. It is typically stable under normal conditions.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
411.44g/mol
Molar mass
411.4400g/mol
Density
1.4500g/cm3
Appearence

Trihexyphenidyl iodide typically appears as a white to off-white crystalline powder. It is commonly used in the medical field.

Comment on solubility

Solubility of Trimethyl-[2-[phenyl-[3-(trifluoromethyl)phenyl]methoxy]ethyl]ammonium Iodide

The solubility of the compound trimethyl-[2-[phenyl-[3-(trifluoromethyl)phenyl]methoxy]ethyl]ammonium iodide can be quite intriguing due to its unique chemical structure. Here are some key points regarding its solubility:

  • Polarity: The presence of the iodide anion contributes to the overall polarity of the compound, which often enhances solubility in polar solvents like water.
  • Hydrophobic Characteristics: The phenyl and trifluoromethyl groups introduce hydrophobic characteristics, potentially limiting the solubility in aqueous solutions.
  • Ammonium Ion: The trimethylammonium group can provide solubility in organic solvents, particularly those that are also polar, due to its ability to interact with solvent molecules.
  • Solvent Specificity: Generally, such ammonium salts exhibit increased solubility in alcohols and other organic solvents, while solubility in water may vary.

In summary, although trimethyl-[2-[phenyl-[3-(trifluoromethyl)phenyl]methoxy]ethyl]ammonium iodide has polar features that suggest some solubility in polar solvents, its hydrophobic components could restrict its solubility in water. The overall behavior is a balance of these conflicting interactions, making it a compound of interest in solubility studies.

Interesting facts

Interesting Facts About Trimethyl-[2-[phenyl-[3-(trifluoromethyl)phenyl]methoxy]ethyl]ammonium Iodide

Trimethyl-[2-[phenyl-[3-(trifluoromethyl)phenyl]methoxy]ethyl]ammonium iodide is a fascinating compound with a wide range of applications and characteristics that make it notable in the field of chemistry. Here are some interesting points to consider:

  • Quaternary Ammonium Compound: This compound belongs to the class of quaternary ammonium salts, which are known for their unique properties due to the positively charged nitrogen atom.
  • Versatile Applications: It is often used in various fields such as pharmaceuticals, biochemistry, and chemical synthesis. Its ability to act as a phase transfer catalyst is particularly useful in organic reactions.
  • Trifluoromethyl Influence: The presence of the trifluoromethyl group (–CF3) significantly alters the chemical behavior of the compound, making it more lipophilic and enhancing its biological activity.
  • Biological Importance: Compounds like this often play critical roles in drug design. The unique structural features can lead to improved binding affinity for biological targets, potentially resulting in new therapeutics.
  • Complex Molecular Structure: The intricate arrangement of phenyl and methoxy groups contributes to the compound's chemical reactivity and stability. Understanding this complexity can lead to innovative synthetic pathways.

As highlighted by many researchers in the field, compounds like trimethyl-[2-[phenyl-[3-(trifluoromethyl)phenyl]methoxy]ethyl]ammonium iodide remind us that:

"The beauty of chemistry lies in the endless possibilities of molecular interactions and applications."

The study and application of trimethyl-[2-[phenyl-[3-(trifluoromethyl)phenyl]methoxy]ethyl]ammonium iodide not only expands our understanding of chemical behavior but also contributes to advancements in various scientific disciplines.

Synonyms
(2-(alpha-(alpha,alpha,alpha-Trifluoro-m-tolyl)benzyloxy)ethyl)trimethylammonium iodide
1868-72-0
Ammonium, (2-(alpha-(alpha,alpha,alpha-trifluoro-m-tolyl)benzyloxy)ethyl)trimethyl-, iodide
Ammonium, trimethyl(2-((alpha-phenyl-m-(trifluoromethyl)benzyl)oxy)ethyl)-, iodide
DTXSID70940146
N,N,N-Trimethyl-2-{phenyl[3-(trifluoromethyl)phenyl]methoxy}ethan-1-aminium iodide