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Memantine

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Identification
Molecular formula
C12H21N
CAS number
19982-08-2
IUPAC name
trimethyl-[3-[4-[2-(1-methylindol-3-yl)ethyl]pyridin-1-ium-1-yl]propyl]ammonium;dihydroxide
State
State

At room temperature, Memantine is in a solid state, specifically as a crystalline powder. It is stable under ordinary conditions of use and storage.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
215.33g/mol
Molar mass
215.7550g/mol
Density
1.1580g/cm3
Appearence

Memantine typically appears as a white to off-white crystalline powder with no significant odor. It is soluble in water and alcohol, making it suitable for formulation into various dosage forms for medical use.

Comment on solubility

Solubility of Trimethyl-[3-[4-[2-(1-methylindol-3-yl)ethyl]pyridin-1-ium-1-yl]propyl]ammonium Dihydroxide

The solubility of trimethyl-[3-[4-[2-(1-methylindol-3-yl)ethyl]pyridin-1-ium-1-yl]propyl]ammonium dihydroxide can exhibit intriguing characteristics due to its complex structure and the presence of positively charged nitrogen atoms.

Generally, the solubility of ionic compounds in water can be influenced by several factors:

  • Charge and Size: The presence of quaternary ammonium groups often enhances solubility in polar solvents due to their ionic nature.
  • Hydrogen Bonding: The dihydroxide portion can contribute to hydrogen bonding, which may increase interaction with water molecules.
  • Hydrophobic Interactions: The indole ring in the compound may introduce hydrophobic characteristics, potentially reducing overall solubility in strictly aqueous environments.

In summary, while the ionic dihydroxide part suggests significant solubility in polar solvents like water, the hydrophobic portions from the indole ring may create some resistance to full solvation. Thus, the actual solubility can vary widely depending on the solvent used and environmental conditions. As such, it is important to perform solubility tests under specified conditions to determine the exact behavior of this compound in solution.

Interesting facts

Interesting Facts about Trimethyl-[3-[4-[2-(1-methylindol-3-yl)ethyl]pyridin-1-ium-1-yl]propyl]ammonium Dihydroxide

This compound, known for its complex structure and unique properties, belongs to a class of compounds that can exhibit fascinating behaviors in biochemical systems. Here are some essential insights:

  • Structural Diversity: The compound features a trimethylammonium group combined with an indole moiety, which is known for its role in biological systems. Indoles are often found in many natural compounds, including hormones and neurotransmitters.
  • Quaternary Ammonium Ion: The presence of the quaternary ammonium ion contributes to the compound's functionality in various applications, including its potential as a surfactant or a phase transfer catalyst.
  • Biological Activity: Due to the incorporation of an indolyl structure, there is potential for interesting biological activity, such as antimicrobial or anticancer properties. These characteristics could be crucial for pharmaceutical development.
  • Research Goldmine: Compounds similar to this one are often used in research related to cell signaling and drug delivery systems, highlighting their significance in medicinal chemistry.

One compelling aspect of trimethyl-[3-[4-[2-(1-methylindol-3-yl)ethyl]pyridin-1-ium-1-yl]propyl]ammonium dihydroxide is its ability to interact with biological membranes, potentially facilitating the transport of drugs across lipid bilayers. Its intricate design allows for tailored modifications, making it an exciting candidate for further study!

In the words of a renowned chemist: "The complexity and beauty of chemical compounds like this one remind us that even the tiniest structure can hold vast potential for innovation and discovery."