Skip to main content

Varenicline

ADVERTISEMENT
Identification
Molecular formula
C13H13N3O
CAS number
249296-44-4
IUPAC name
trimethyl-[4-(2-oxopyrrolidin-1-yl)but-3-ynyl]ammonium
State
State

At room temperature, Varenicline is typically in a solid state, making it suitable for formulation into tablets or capsules for oral administration.

Melting point (Celsius)
141.50
Melting point (Kelvin)
414.65
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
518.23g/mol
Molar mass
518.2250g/mol
Density
1.1500g/cm3
Appearence

Varenicline typically appears as a white to off-white crystalline solid, reflecting its purity and chemical structure. Its solid form allows for easier handling and processing in pharmaceutical manufacturing.

Comment on solubility

Solubility of Trimethyl-[4-(2-oxopyrrolidin-1-yl)but-3-ynyl]ammonium

Trimethyl-[4-(2-oxopyrrolidin-1-yl)but-3-ynyl]ammonium is a complex organic compound that displays notable solubility characteristics. Understanding the solubility of such compounds is crucial, as it impacts their usability in applications ranging from pharmaceuticals to industrial processes. Here are some key points regarding its solubility:

  • General Solubility: This compound is likely to exhibit moderate solubility in polar solvents, particularly due to the presence of the ammonium functional group, which tends to enhance solvation in polar environments.
  • Solvent Interaction: Given its structural features, it may also be soluble in organic solvents like acetonitrile and dimethyl sulfoxide (DMSO). The ability to interact favorably with these solvents could stem from its nitrogen-containing moiety.
  • Temperature Dependence: As with many organic compounds, solubility may increase with temperature; thus, heating the solvent may assist in achieving a higher dissolution rate.
  • Diluents Impact: When mixed with other compounds, solubility can change dramatically based on the nature of the diluents used. Non-polar solvents may render it less soluble.
  • pH Influence: Altering the pH of the solution could also impact solubility, as ionic compounds often have different solubility profiles at varying pH levels.

In summary, the solubility of trimethyl-[4-(2-oxopyrrolidin-1-yl)but-3-ynyl]ammonium is multifaceted and influenced by various factors, underscoring the importance of solvent selection and environmental conditions in practical applications. Always consider these elements when working with this compound to ensure optimal results.

Interesting facts

Interesting Facts about Trimethyl-[4-(2-Oxopyrrolidin-1-yl)but-3-ynyl]ammonium

Trimethyl-[4-(2-oxopyrrolidin-1-yl)but-3-ynyl]ammonium is a fascinating compound that falls within the scope of organic chemistry and serves as a remarkable example of ammonium derivatives. This compound showcases the unique properties and functionalities that nitrogen-containing groups can impart to organic molecules. Here are some engaging aspects of this compound:

  • Nitrogen Dynamics: The presence of the trimethylammonium group plays a crucial role in enhancing the solubility of the compound in polar solvents, making it an interesting subject for studies in organic synthesis and reaction mechanisms.
  • Synthetic Versatility: Due to its structural motif, this compound can serve as a precursor for further chemical modifications, allowing chemists to explore new related compounds and potentially discover novel materials.
  • Biological Implications: The inclusion of the 2-oxopyrrolidine unit suggests potential applications in medicinal chemistry, particularly in the design of pharmacologically relevant molecules.
  • Reactivity Profiles: Understanding the reactivity of compounds like this one can lead to insights in creating effective catalysts and intermediates in complex chemical reactions.
  • Structure-Activity Relationship (SAR): Investigations into how the configurations within this compound affect its biological properties can open doors to the development of new therapeutic agents.

In conclusion, trimethyl-[4-(2-oxopyrrolidin-1-yl)but-3-ynyl]ammonium exemplifies just how intricate organic compounds can be, revealing layers of complexity that challenge and inspire chemists. As one explores the depths of such compounds, the potential for innovation continues to grow, paving the way for exciting discoveries in both theoretical and applied chemistry.