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Propidium iodide

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Identification
Molecular formula
C27H34N4I2
CAS number
25535-16-4
IUPAC name
trimethyl-[4-[4-(trimethylammonio)phenyl]phenyl]ammonium
State
State

At room temperature, propidium iodide generally exists as a solid powder which is used in various solution-based applications.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
668.40g/mol
Molar mass
668.4000g/mol
Density
1.9927g/cm3
Appearence

Propidium iodide is a red-fluorescent, intercalating agent that exhibits an orange/red color in solution when used in the context of biological experiments. In powdered form, it is typically a fine red solid.

Comment on solubility

Solubility of Trimethyl-[4-[4-(trimethylammonio)phenyl]phenyl]ammonium

Trimethyl-[4-[4-(trimethylammonio)phenyl]phenyl]ammonium is a quaternary ammonium compound that exhibits unique solubility properties:

  • Water Solubility: As a quaternary ammonium salt, it is generally expected to have good solubility in water due to the presence of multiple positively charged ammonium groups.
  • Organic Solvents: This compound may also dissolve well in polar organic solvents because of its hydrophobic hydrocarbon chains attached to the phenyl rings.
  • pH Sensitivity: The solubility can be influenced by the pH of the solution, which can alter the ionization state of the ammonium groups, impacting its overall solubility profile.

As we delve deeper into its solubility characteristics, it becomes apparent that:

  1. Electrostatic Interactions: The positive charge on the nitrogen atoms leads to strong interactions with polar solvents, enhancing solubility.
  2. Hydrophobic Effects: The phenyl groups make the compound partially hydrophobic, which could restrict solubility in purely aqueous environments.

In conclusion, the solubility of trimethyl-[4-[4-(trimethylammonio)phenyl]phenyl]ammonium is a balance between its charged ammonium groups and the hydrophobic character of its phenyl rings, making it versatile in both aqueous and organic environments depending on the conditions.

Interesting facts

Interesting Facts about Trimethyl-[4-[4-(trimethylammonio)phenyl]phenyl]ammonium

Trimethyl-[4-[4-(trimethylammonio)phenyl]phenyl]ammonium is a fascinating compound that piques the interest of chemists and researchers alike. Here are some intriguing aspects of this compound:

  • Quaternary Ammonium Compound: This compound belongs to the class of quaternary ammonium compounds, which are known for their cationic behavior. They often play essential roles in both industrial and biological contexts.
  • Applications in Biotechnology: Compounds like this one are frequently utilized in drug delivery systems, where their amphiphilic properties aid in crossing biological membranes, enhancing the bioavailability of therapeutic agents.
  • Surfactant Properties: Trimethyl-[4-[4-(trimethylammonio)phenyl]phenyl]ammonium exhibits surfactant characteristics which make it valuable in formulating products like detergents, fabric softeners, and emulsifiers.
  • Role in Antimicrobial Activity: Research has shown that quaternary ammonium compounds can possess significant antimicrobial properties, making them beneficial in disinfection procedures and antimicrobial coatings.
  • Environmental Impact: While these compounds are immensely useful, there are ongoing studies to understand their environmental impact and biodegradability, which is crucial for sustainable application.

In summary, trimethyl-[4-[4-(trimethylammonio)phenyl]phenyl]ammonium serves as a testament to the complexity and utility of modern chemistry, bridging industrial applications and biological significance. As researchers continue to explore its properties and interactions, this compound may unlock new avenues for innovation.

Synonyms
SCHEMBL13567373