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Hexamethonium bromide

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Identification
Molecular formula
(C12H30N2)Br2
CAS number
55-97-0
IUPAC name
trimethyl-[5-(trimethylammonio)pentyl]ammonium;dibromide
State
State
At room temperature, hexamethonium bromide is in a solid state, generally found as a crystalline powder.
Melting point (Celsius)
274.00
Melting point (Kelvin)
547.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
444.19g/mol
Molar mass
0.0000g/mol
Density
1.0450g/cm3
Appearence
Hexamethonium bromide is typically a white crystalline powder.
Comment on solubility

Solubility of Trimethyl-[5-(trimethylammonio)pentyl]ammonium Dibromide

Trimethyl-[5-(trimethylammonio)pentyl]ammonium dibromide, a quaternary ammonium salt, exhibits some intriguing solubility properties. Its solubility can generally be characterized by the following points:

  • Solvent Polarity: The compound tends to be soluble in polar solvents such as water and alcohols due to its ionic nature, attributed to the presence of the ammonium group and bromide ions.
  • Ionic Interaction: Because of its quaternary ammonium structure, it interacts favorably with other polar molecules, which enhances its solubility in aqueous environments.
  • Hydration Effects: The ability of water to stabilize the ionic components by solvation also contributes significantly to its solubility.
  • Temperature Dependency: Like many salts, solubility may increase with temperature, making it more soluble at elevated temperatures.

In summary, the solubility of trimethyl-[5-(trimethylammonio)pentyl]ammonium dibromide is largely influenced by its ionic characteristics and the polarity of the solvent used. As stated, "like dissolves like," reflects the tendency of this compound to favorably dissolve in polar solvents.

Interesting facts

Interesting Facts About Trimethyl-[5-(trimethylammonio)pentyl]ammonium Dibromide

Trimethyl-[5-(trimethylammonio)pentyl]ammonium dibromide is a fascinating quaternary ammonium compound that has drawn significant interest in various fields of chemistry and biochemistry. Here are some interesting points to consider:

  • Quaternary Ammonium Compounds: This compound belongs to a larger family of quaternary ammonium compounds, which are known for their ability to function as surfactants, antimicrobial agents, and phase transfer catalysts.
  • Charge and Solubility: Being quaternary in nature, it carries a permanent positive charge, enhancing its solubility in polar solvents. This property allows it to interact readily with both hydrophilic and hydrophobic environments, making it suitable for a variety of applications.
  • Biological Significance: Compounds like trimethyl-[5-(trimethylammonio)pentyl]ammonium dibromide can mimic phospholipids and interact with cell membranes. This property can potentially influence cell signaling and membrane dynamics.
  • Application in Drug Delivery: Due to its positive charge, it can facilitate the transport of drugs across membrane barriers, enhancing bioavailability—a key consideration in medicinal chemistry and pharmacology.
  • Research Interest: Scientists are exploring its applications in nanotechnology and materials science for the development of drug delivery systems and antimicrobial surfaces.

In the words of a well-known chemist, "The study of quaternary ammonium compounds opens new avenues in the design of therapeutic agents." As we continue to uncover the potential of this compound, it becomes clear that trimethyl-[5-(trimethylammonio)pentyl]ammonium dibromide holds promise for advancing our understanding of biochemical interactions and material design.

Synonyms
Pentamethonium bromide
541-20-8
Lytensium
Penthonium
Pentamethonium dibromide
Bromuro de pentametonio
Bromure de pentamethonium
Pentamethonii bromidum
Pentametonio bromuro
Pentametonio bromuro [DCIT]
EINECS 208-771-7
Pentamethonium bromide [INN:BAN]
Pentamethylenebis(trimethylammonium bromide)
UNII-0UX03A6JJC
Pentamethonii bromidum [INN-Latin]
Bromuro de pentametonio [INN-Spanish]
NSC 148343
Bromure de pentamethonium [INN-French]
alpha,omega-Bis(trimethylammonium)pentane dibromide
AI3-20833
NSC-148343
CHEBI:134839
PENTAMETHONIUM BROMIDE [MI]
1,5-dibromohexamethylpentaneammonium
PENTAMETHONIUM BROMIDE [INN]
PENTAMETHONIUM BROMIDE [MART.]
AMMONIUM, PENTAMETHYLENEBIS(TRIMETHYL-, DIBROMIDE
PENTAMETHONIUM BROMIDE [WHO-DD]
1,5-Pentanediaminium, N,N,N,N',N',N'-hexamethyl-, dibromide
Pentamethylenebis[trimethylammonium bromide]
1,5-Pentanediaminium, N,N,N,N',N',N'-hexamethyl-, dibromide (9CI)
N,N,N,N',N',N'-hexamethyl-1,5-pentanediaminium dibromide
N,N,N,N',N',N'-hexamethylpentane-1,5-bis(aminium) dibromide
Pentamethonii bromidum (INN-Latin)
Bromuro de pentametonio (INN-Spanish)
PENTAMETHONIUM BROMIDE (MART.)
Bromure de pentamethonium (INN-French)
N(1),N(1),N(1),N(5),N(5),N(5)-hexamethylpentane-1,5-bis(aminium) dibromide
pentamAthonium (cation)
208-771-7
0UX03A6JJC
C 5
N1,N1,N1,N5,N5,N5-hexamethylpentane-1,5-diaminium bromide
PENTAMETHIONIUM BROMIDE
C 5 (VAN)
Pentamethoniumbromid
C 5; Lytensium; Pentamethonium dibromide; Penthonium; alpha,omega-Bis(trimethylammonium)pentane dibromide
SCHEMBL61797
CHEMBL2107007
trimethyl-[5-(trimethylazaniumyl)pentyl]azanium,dibromide
GJVFBWCTGUSGDD-UHFFFAOYSA-L
MFCD00050191
AKOS040747260
DB-052488
NS00042747
Q27237276
trimethyl-[5-(trimethylazaniumyl)pentyl]azanium;dibromide
1,5-PENTANEDIAMINIUM, N1,N1,N1,N5,N5,N5-HEXAMETHYL-, BROMIDE (1:2)
C 5; Lytensium; Pentamethonium dibromide; Penthonium; ,-Bis(trimethylammonium)pentane dibromide
C-5