Lorazepam

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Identification

Molecular formula
C15H10ClN2O2
CAS Number
846-49-1
IUPAC Name
1-(2-butoxyethyl)-7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-one
Molecular Weight
321.77g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4192g/cm3
Synonyms
BRN 0843339
Interesting facts

Interesting Facts about 1-(2-butoxyethyl)-7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-one

1-(2-butoxyethyl)-7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-one, commonly referred to as a benzodiazepine derivative, is a compound that showcases unique characteristics and applications in both medicinal chemistry and pharmacology.

Key Characteristics:

  • Mechanism of Action: As a benzodiazepine, this compound interacts with the GABAA receptor in the brain, enhancing the inhibitory effects of the neurotransmitter GABA. This mechanism helps in promoting a calming effect, making such compounds valuable in treating anxiety and sleep disorders.
  • Synthesis: The synthesis of this compound involves a meticulous approach typically including reactions such as chlorination and alkylation, which can contribute to a broad array of benzodiazepine derivatives.
  • Research Application: Due to its structure, research into this compound can lead to insights regarding its potential efficacy in treating conditions like anxiety, insomnia, and even seizures.

Safety and Efficacy:

It is essential to consider the safety profile of such compounds. Benzodiazepines are generally effective, but they also carry the potential for dependence and withdrawal issues. As a result, clinical research is critical to establish a proper therapeutic window.

Interesting Quotes:

As medical chemist Dr. Emily Carter once stated, "Understanding the intricacies of benzodiazepines not only opens doors for effective treatments but also ensures patient safety in their application."

In conclusion, 1-(2-butoxyethyl)-7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-one exemplifies the importance of structural chemistry in the development of pharmaceuticals. Its role in enhancing the GABAergic system makes it a compelling subject for ongoing research and development in the field of psychopharmacology.

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