Clotrimazole

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Identification

Molecular formula
C22H17Cl2N3O
CAS Number
23593-75-1
IUPAC Name
1-(2,4-dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-imidazol-1-yl-ethanimine
Molecular Weight
344.64g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3820g/cm3
Synonyms
64211-45-6
Interesting facts

Interesting Facts about 1-(2,4-Dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-imidazol-1-yl-ethanimine

This compound, known for its extensive applications in medicinal chemistry, has sparked interest among scientists due to its intriguing structure and potential biochemical interactions. Here are some engaging details:

  • Pharmacological Properties: The compound exhibits notable activity against a range of biological targets, making it a candidate for further investigation in pharmaceuticals.
  • Chlorine Atoms: The presence of two chlorine atoms in the phenyl rings is not merely decorative; it contributes to the compound's lipophilicity, enhancing membrane permeability which is vital for drug design.
  • Imidazole Ring: The imidazole moiety in the structure is key in many biological processes, particularly as a part of enzyme systems. It is known for its role in catalyzing various biological reactions.
  • Synthetic Pathway: The synthesis of this compound involves several steps that can be optimized for yield and purity, providing a fertile ground for discussions regarding synthetic methodology in organic chemistry.
  • Structure-Activity Relationship (SAR): Variations in the structure can lead to significant changes in biological activity, making it an excellent candidate for SAR studies. This can help in understanding how slight modifications can enhance efficacy or reduce toxicity.

As with many compounds in medicinal chemistry, the gap between theoretical potential and practical application can be significant. Understanding both structure and function is crucial for advancing drug development. This compound exemplifies the synergy of chemistry and biology, demonstrating the deep connections between molecular structure and biological function.

Researchers and students alike can appreciate the blend of creativity and science involved in exploring such compounds. "The only way to do great work is to love what you do"—a quote from Steve Jobs that resonates well with the journey of scientific discovery!

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